Results 51 to 60 of about 13,291 (204)

Functional deficits precede structural lesions in mice with high-fat diet-induced diabetic retinopathy [PDF]

, 2016
Obesity predisposes to human type 2 diabetes, the most common cause of diabetic retinopathy. To determine if high-fat diet–induced diabetes in mice can model retinal disease, we weaned mice to chow or a high-fat diet and tested the hypothesis that diet ...
Bligard, Gregory W, Lukasiewicz, Peter, Rajagopal, Rithwick, Semenkovich, Clay F, Yin, Li, Zhang, Sheng   +5 more
core   +2 more sources

Salvia coccinea and Apigenin: A Natural Treasure of Lamiaceae in Pharmacological Innovation

Food Science &Nutrition, Volume 14, Issue 2, February 2026.
Salvia coccinea is rich in bioactive phytochemicals, notably the flavonoid apigenin, offering strong antioxidant, anti‐inflammatory, and antimicrobial effects. By modulating inflammatory and oxidative pathways, it shows potential for managing chronic diseases.
Muhammad Usman Khalid, Muhammad Tauseef Sultan, Muhammad Maaz, Shehnshah Zafar, Anum Shoukat, Nudrat Khursheed, Matteo Bordiga, Amna Junaid   +7 more
wiley   +1 more source

Chemotherapy-related complications in the kidneys and collecting system: an imaging perspective [PDF]

, 2015
Nephrotoxicity is a common adverse effect of many chemotherapeutic agents. The agents most commonly associated with chemotherapy-associated nephrotoxicity are methotrexate, semustine, streptozocin, mithramycin, and cisplatin.
Goodwin, Scott C., Gulati, Rajesh, Jia, Jemianne Bautista, Lall, Chandana, Lamba, Ramit, Tirkes, Temel   +5 more
core   +1 more source

Cinnamaldehyde attenuates streptozocin-induced diabetic osteoporosis in a rat model by modulating netrin-1/DCC-UNC5B signal transduction

Frontiers in Pharmacology
Background: Cinnamaldehyde (CMD) is a major functional component of Cinnamomum verum and has shown treatment effects against diverse bone diseases. This study aimed to assess the anti-diabetic osteoporosis (DOP) potential of diabetes mellitus (DM) and to
Songjie Ji, Songjie Ji, Bingjia Zhao, Yuan Gao, Jun Xie, Huijun Han, Qunli Wu, Dan Yang   +7 more
doaj   +1 more source

Comparative evaluation of pancreatic histopathology of rats treated with olanzapine, risperidone and streptozocin

Brazilian Journal of Pharmaceutical Sciences, 2018
Olanzapine and risperidone are widely prescribed atypical antipsychotics used in the treatment of schizophrenia and various other psychiatric disorders. Both of these drugs have been extensively reported to cause Type 2 diabetes mellitus and pancreatitis,
Rehmat Shah, Fazal Subhan, Sayed Mohammad Sultan, Gowhar Ali, Ihsan Ullah, Sami Ullah   +5 more
doaj   +1 more source

Antidiabetic Effect of Collagen Peptides from Harpadon nehereus Bones in Streptozotocin-Induced Diabetes Mice by Regulating Oxidative Stress and Glucose Metabolism

Marine Drugs, 2023
Oxidative stress and abnormal glucose metabolism are the important physiological mechanisms in the occurrence and development of diabetes. Antioxidant peptides have been reported to attenuate diabetes complications by regulating levels of oxidative ...
Qianxia Lin, Yueping Guo, Jie Li, Shuqi He, Yan Chen, Huoxi Jin   +5 more
doaj   +1 more source

The long-acting somatostatin analogue octreotide alleviates symptoms by reducing posttranslational conversion of prepro-glucagon to glucagon in a patient with malignant glucagonoma, but does not prevent tumor growth [PDF]

, 1994
A 52-year-old female with metastatic glucagonoma secreting glucagon and chromogranin A was treated with the somatostatin analogue octreotide for 2 years without any additional tumor-reducing interventions. Before therapy plasma glucagon was above 8 μg/l (
Jockenhövel, F. (F.), Krenning, E.P. (Eric), Lamberts, S.W.J. (Steven), Lederbogen, S. (S.), Olbricht, T. (T.), Reinwein, D. (D.), Schmidt-Gayk, H. (H.)   +6 more
core   +2 more sources

Indications for Surgical Resection in Patients With Neuroendocrine Tumor Liver Metastases: An Intensive Surgical Experience of a High‐Volume Center

Annals of Gastroenterological Surgery, Volume 10, Issue 1, Page 219-228, January 2026.
In patients with NELM, those with < 8 liver metastases and G1/2 tumors are the favorable candidates for liver resection. The important point of this study is that the patients who do not meet the above criteria should be considered for multidisciplinary treatment because of their extremely shorter recurrence‐free period.
Daisuke Asano, Toshitaka Sugawara, Keiichi Akahoshi, Shotaro Gan, Shohei Motohashi, Shuichi Watanabe, Yoshiya Ishikawa, Hiroki Ueda, Atsushi Kudo, Daisuke Ban   +9 more
wiley   +1 more source

The influence of anberr-antitox and silymarin on oxidative phosphorilation and lipid peroxide oxidation in rat’s liver in the experimental diabetes mellitus

Бюллетень сибирской медицины, 2006
The model of diabetes mellitus caused by intraperitoneal injection of streptozotocin in dose of 65 mg/kg in experiment on rats was accompanied by alternation of mitochondrial functions (hyperactivation of respiration and disconnection of oxidative ...
K. A. Eskina, K. Yu. Vasilyev
doaj   +1 more source

Seasonal Variation in Leaf Growth and Antioxidant Content of Moringa oleifera Cultivated at Buenos Aires, Argentina [PDF]

, 2016
The properties and applications of Moringa oleifera are so vast that it is called the "miracle tree". The objective of this work is to study the seasonal variations in the leaf antioxidant content and the scavenging activity on DPPH radicals in ...
Arena, Miriam Elisabet, Radice, Silvia
core   +1 more source