Results 61 to 70 of about 18,167 (294)

Is there a role for cannabidiol in obesity, metabolic syndrome and binge eating?

open access: yesBritish Journal of Pharmacology, EarlyView.
Cannabidiol (CBD) is one of the most abundant phytocannabinoids isolated from the Cannabis sativa plant. CBD is a lipophilic, non‐intoxicating substance that differently from Δ9‐tetrahydrocannabinol (Δ9‐THC) does not present the typical profile of a drug of abuse.
Luca Botticelli   +7 more
wiley   +1 more source

Deficits in trabecular bone microarchitecture in young women with Type 1 diabetes mellitus [PDF]

open access: yes, 2015
Context: The pathophysiological mechanism of increased fractures in young adults with Type 1 Diabetes Mellitus (T1DM) is unclear. Objective: Case:control study of trabecular bone microarchitecture and vertebral marrow adiposity in young women with ...
Al-Daghri   +49 more
core   +1 more source

Is Micronucleus Assay a Suitable Biomarker for Evaluating the Cancer Risk in Professionals Exposed to Antineoplastic Drugs? A Systematic Review

open access: yesJournal of Applied Toxicology, Volume 46, Issue 3, Page 733-753, March 2026.
ABSTRACT The widespread use of antineoplastic drugs in cancer treatment has led to significant concerns regarding the potential health risks posed to healthcare professionals involved in the preparation, administration, and handling of these chemical compounds, including genotoxicity.
Thiago Guedes Pinto   +6 more
wiley   +1 more source

Secretome effect of adipose tissue-derived stem cells cultured two-dimensionally and three-dimensionally in mice with streptozocin induced type 1 diabetes

open access: yesCurrent Research in Pharmacology and Drug Discovery, 2021
Aims: To analyze therapeutic potential of the conditioned medium from adipose tissue-derived stem cells (ASC) cultivated in 2D (CM-2D) and 3D (CM-3D) models, in mice with Type 1 diabetes (T1D) induced by streptozotocin.
Isabelle Dias   +7 more
doaj   +1 more source

Chemotherapy-related complications in the kidneys and collecting system: an imaging perspective [PDF]

open access: yes, 2015
Nephrotoxicity is a common adverse effect of many chemotherapeutic agents. The agents most commonly associated with chemotherapy-associated nephrotoxicity are methotrexate, semustine, streptozocin, mithramycin, and cisplatin.
Goodwin, Scott C.   +5 more
core   +1 more source

Indications for Surgical Resection in Patients With Neuroendocrine Tumor Liver Metastases: An Intensive Surgical Experience of a High‐Volume Center

open access: yesAnnals of Gastroenterological Surgery, Volume 10, Issue 1, Page 219-228, January 2026.
In patients with NELM, those with < 8 liver metastases and G1/2 tumors are the favorable candidates for liver resection. The important point of this study is that the patients who do not meet the above criteria should be considered for multidisciplinary treatment because of their extremely shorter recurrence‐free period.
Daisuke Asano   +9 more
wiley   +1 more source

Dynamics of heart rate variability in rats with streptozotocin-induced diabetes

open access: yesСахарный диабет, 2019
Background: Diabetes mellitus (DM) has a negative impact on all organs. This is due to insufficiency of blood supply and the disruption of the trophic function of the nervous system.
Maria P. Morozova   +10 more
doaj   +1 more source

Functional deficits precede structural lesions in mice with high-fat diet-induced diabetic retinopathy [PDF]

open access: yes, 2016
Obesity predisposes to human type 2 diabetes, the most common cause of diabetic retinopathy. To determine if high-fat diet–induced diabetes in mice can model retinal disease, we weaned mice to chow or a high-fat diet and tested the hypothesis that diet ...
Bligard, Gregory W   +5 more
core   +2 more sources

C‐reactive protein exacerbates epithelial‐mesenchymal transition through Wnt/β‐catenin and ERK signaling in streptozocin‐induced diabetic nephropathy

open access: yesThe FASEB Journal, 2019
Previous studies have reported the pathogenic role of C‐reactive protein (CRP) during diabetic kidney disease (DKD) in human CRP transgenic and Crp−/− mice.
Lin Zhang   +8 more
semanticscholar   +1 more source

Anti‐Diabetic Effects of Ayanin, a Flavonoid Compound, in STZ/HFD‐Induced Diabetic Mice by Upregulating GLUT4 and Suppressing Macrophage‐Driven Inflammation in Adipose Tissues

open access: yesFood Science &Nutrition, Volume 14, Issue 1, January 2026.
Ayanin, a flavonoid extracted from red wine grapes, has demonstrated efficacy in ameliorating hyperglycemia, dyslipidemia, and insulin resistance through directly targeting the AMPKα/GLUT4 and AMPKα/CPT‐1α signaling pathways in metabolic tissues.
Yibing Lv   +10 more
wiley   +1 more source

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