Results 11 to 20 of about 181,208 (343)

Morchella esculenta mushroom polysaccharide attenuates diabetes and modulates intestinal permeability and gut microbiota in a type 2 diabetic mice model

Frontiers in Nutrition, 2022
Type 2 diabetes mellitus (T2DM) is a health issue that causes serious worldwide economic problems. It has previously been reported that natural polysaccharides have been studied with regard to regulating the gut microbiota, which plays an important role ...
Ata Ur Rehman, Nimra Zafar Siddiqui, Nabeel Ahmed Farooqui, Gulzar Alam, Aneesa Gul, Bashir Ahmad, Muhammad Asim, Asif Iqbal Khan, Yi Xin, Wang Zexu, Hyo Song Ju, Wang Xin, Sun Lei, Liang Wang   +13 more
doaj   +1 more source

Influence of N-acetylcysteine on pituitary-gonadal axis hormones and protamine expression level in streptozotocin-induced diabetic male rats

Asian Pacific Journal of Reproduction, 2020
Objective: To study the influence of N-acetylcysteine on the pituitary-gonadal axis hormones and protamine expression level in streptozotocin-induced diabetic male rats. Methods: Forty-two adult male Wistar rats were divided into 6 groups, with 7 rats in
Maryam Hassanzadeh Moghadam, Mehrdad Shariati, Sirous Naeimi, Mohammad Amin Edalatmanesh   +3 more
doaj   +1 more source

Insights in diabetes: Molecular mechanisms-Protectin DX, an anti-inflammatory and a stimulator of inflammation resolution metabolite of docosahexaenoic acid, protects against the development of streptozotocin-induced type 1 and type 2 diabetes mellitus in male Swiss albino mice

Frontiers in Endocrinology, 2023
Our previous studies revealed that certain endogenous low molecular weight lipids have potent anti-diabetic actions. Of all, arachidonic acid (AA) and its anti-inflammatory and inflammation resolving metabolite lipoxin A4 (LXA4) are the most potent anti ...
Poorani Rengachar, Poorani Rengachar, Sailaja Polavarapu, Sailaja Polavarapu, Undurti N. Das, Undurti N. Das, Undurti N. Das   +6 more
doaj   +1 more source

Triphala Churna—A Traditional Formulation in Ayurveda Mitigates Diabetic Neuropathy in Rats

Frontiers in Pharmacology, 2021
Neuropathy is a common complication of diabetes affecting a large number of people worldwide. Triphala churna is a formulation mentioned in Ayurveda-a traditional system of medicine. It is a simple powder formulation consisting of powders of three fruits,
Sachin V. Suryavanshi, Kalyani Barve, Veeranjaneyulu Addepalli, Sachin V. Utpat, Yogesh A. Kulkarni   +4 more
doaj   +1 more source

LIPID METABOLISM IN DIABETIC RATS AS AFFECTED BY CANOLA AND MUSTARD SEED SPROUTS [PDF]

Arab Universities Journal of Agricultural Sciences, 2018
Canola (Brassica juncea L.) and mustard (Sinapis alba L.) seed sprout effects on diabetic rats  have no available information and to clarify their effects, both sprouts were investigated in streptozotocin (STZ) induced diabetic and normal rats. Rats were
Hanaa Amer, Tahany Aly, K. Tobgy, M. Abdallah, N. El-Shahat   +4 more
doaj   +1 more source

Quercetin liposomes ameliorate streptozotocin-induced diabetic nephropathy in diabetic rats

Scientific Reports, 2020
The effects of quercetin liposomes (Q-PEGL) on streptozotocin (STZ)-induced diabetic nephropathy (DN) was investigated in rats. Male Sprague Dawley rats were used to establish a STZ induced DN model.
L. Tang, Ke Li, Yan Zhang, Huifang Li, Ankang Li, Yuancheng Xu, B. Wei   +6 more
semanticscholar   +1 more source

Peripheral Neuropathy Presents Similar Symptoms and Pathological Changes in Both High-Fat Diet and Pharmacologically Induced Pre- and Diabetic Mouse Models

Life, 2021
The objective of the study was to compare the effects of experimentally induced type 1 or type 2 diabetes (T1D or T2D) on the functional, structural and biochemical properties of mouse peripheral nerves. Eight-week-old C57BL/6 mice were randomly assigned
Julia Jaroslawska, Agnieszka Korytko, Kamila Zglejc-Waszak, Tomasz Antonowski, Andrzej S. Pomianowski, Krzysztof Wasowicz, Joanna Wojtkiewicz, Judyta K. Juranek   +7 more
doaj   +1 more source

The Influence of Hyperactivity of the Hypothalamic-pituitary-adrenal Axis and Hyperglycemia on the 5-HT2A Receptor-mediated Wet-dog Shake Responses in Rats [PDF]

, 2007
Hyperactivity of the hypothalamic-pituitary-adrenal (HPA) axis induces hyperglycemia and serotonin (5-HT)2A receptor supersensitivity. In the present study, to investigate the effect of hyperglycemia on the function of 5-HT2A receptors, we compared the 5-
Amano, Manabu, Araki, Hiroaki, Gomita, Yutaka, Kawasaki, Hiromu, Kitamura, Yoshihisa, Suemaru, Katsuya, Umeda, Yuichi, Yamaguchi, Takumi   +7 more
core   +1 more source

The mechanism of alloxan and streptozotocin action in B cells of the rat pancreas.

Physiological Research, 2001
Alloxan and streptozotocin are widely used to induce experimental diabetes in animals. The mechanism of their action in B cells of the pancreas has been intensively investigated and now is quite well understood.
T. Szkudelski
semanticscholar   +1 more source

Prognosis of diabetes complications and efficacy of Guiera senegalensis aqueous leaf extract in streptozotocin induced-diabetic rats

Journal of Applied Sciences and Environmental Management, 2018
Diabetes epidemics pose a serious health care problems and a huge burden on the economy of both developed and developing nations. Precise prognosis and the discovery of cost effective drugs for its management would serve as catalyst to economic recovery.
M Osibemhe, O.M. Bello, N Lawal
doaj   +1 more source