DUSP1 Attenuates Renal Injury in Diabetic Nephropathy by Modulating Ferroptosis: Evidence From Animal Experiments [PDF]
ABSTRACT Objective Emerging evidence suggests that ferroptosis contributes significantly to the progression of diabetic nephropathy (DN). This study aimed to explore the potential association between dual specificity phosphatase 1 (DUSP1) and ferroptosis in a streptozotocin‐induced DN rat model.
Liu J, Zhang J, Zou Y, Chen W, Xu J.
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ABSTRACT Sudden death resulting from abdominal aortic aneurysm (AAA) rupture is a highly fatal cardiovascular condition. There remains an urgent need to identify innovative therapeutic strategies capable of decelerating AAA progression and rupture. Although polydatin (PLD) has been consistently shown to exert potent anti‐inflammatory effects in diverse
Zikang Liu +4 more
wiley +1 more source
Modulation of PDX1 gene expression and glycemic control by Citrullus lanatus in experimental type 2 diabetes. [PDF]
Moore AGS, Okoduwa SIR.
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Ricinus Communis: Nutritional Importance, Health Benefits, and Industrial Applications
The current paper summarizes the nutritional composition, phytochemistry, health benefits, safety studies, and applications of castor beans and their oil. Moreover, the diverse bioactive compounds, including saponins, emodins, terpenoids, anthraquinones, flavonoids, steroids, and alkaloids, exhibit therapeutic properties such as antioxidant, anticancer,
Hassan Raza +13 more
wiley +1 more source
Evaluating the impact of intracerebroventricular norepinephrine on spatial memory in rats: Insights into sporadic Alzheimer's pathogenesis. [PDF]
Moien MAS, Saghravanian SJ, Fereidoni M.
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This study presents a self‐powered electronic bandage integrating a triboelectric nanogenerator with flexible interdigital electrodes. The device generates pulsed electric fields that significantly accelerate wound closure in diabetic models by enhancing cell proliferation, reducing inflammation, and promoting angiogenesis, offering a biocompatible and
Zijian Chen +9 more
wiley +1 more source
Novel Function for Endothelial Protease-Activated Receptors in Modulating Insulin Receptor Activity With Implications for Diabetes. [PDF]
Rajala R, Griffin CT.
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Salvia coccinea and Apigenin: A Natural Treasure of Lamiaceae in Pharmacological Innovation
Salvia coccinea is rich in bioactive phytochemicals, notably the flavonoid apigenin, offering strong antioxidant, anti‐inflammatory, and antimicrobial effects. By modulating inflammatory and oxidative pathways, it shows potential for managing chronic diseases.
Muhammad Usman Khalid +7 more
wiley +1 more source
Pandanus amaryllifolius and Tectona grandis Extracts Improve Fetal Outcomes in Streptozotocin-Induced Gestational Diabetes in Rats. [PDF]
Kerdsuknirund S +4 more
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