Results 71 to 80 of about 181,208 (343)
The slow sarco/endoplasmic reticulum Ca2+-ATPase declines independently of slow myosin in soleus muscle of diabetic rats [PDF]
, 2009 The sarcoplasmic reticulum Ca2+-ATPase (SERCA) isoforms are normally expressed in coordination with the corresponding myosin heavy chain (MyHC) isoforms in the fibers of skeletal muscle but this coordination is often disrupted in pathological conditions.
Rácz, Gábor +3 more
core
Microvesicles as vehicles for tissue regeneration: Changing of the guards [PDF]
, 2016 Purpose of Review: Microvesicles (MVs) have been recognised as mediators of stem cell function, enabling and guiding their regenerative effects. Recent Findings: MVs constitute one unique size class of extracellular vesicles (EVs) directly shed from ...
Davies, R. Wayne +3 more
core +1 more source
An In Situ Embedded B‐MOF Sponge With Shape‐Memory for All‐in‐One Diabetic Wound Therapy
Advanced Healthcare Materials, EarlyView.A smart shape‐memory sponge dressing (P1A3@B‐MOF) is developed for accelerated diabetic wound healing. It achieves pH‐responsive corelease of Zn2+ and salvianolic acid B, synergistically providing antibacterial action, repolarizing macrophages to the M2 phenotype, and promoting angiogenesis.
Hai Zhou +11 more
wiley +1 more source
Advanced Healthcare Materials, EarlyView.Zinc‐containing bioactive glass (ZnBG) promotes diabetic wound healing by regulating macrophage extracellular traps (METs). Specifically, ZnBG reduces oxidative stress and inhibits the PAD4 and NLRP3/caspase‐1/GSDMD signaling pathways, thereby suppressing MET formation.
RuiYang Sun +11 more
wiley +1 more source
Antidiabetic and Synergistic Effects Study of Anthocyanin Fraction from Berberis integerrima Fruit on Streptozotocin-Induced Diabetic Rats Model [PDF]
Trends in Pharmaceutical Sciences, 2016 Introduction: Diabetes mellitus is a complex endocrine disorder. There is serious attempt to realize antidiabetic compound from natural sources to use with other drugs for reduction of diabetes complication. Materials and Methods: Present study is based
Zahra Sabahi +3 more
doaj
Brazilian Journal of Medical and Biological Research, 1998 Nitric oxide synthase activity was measured in Langerhans islets isolated from control and streptozotocin diabetic rats. The activity of the enzyme was linear up to 150 µg of protein from control rats and was optimal at 0.1 µM calcium, when it was ...
T.M. Fonovich de Schroeder +3 more
doaj +1 more source
Advanced Healthcare Materials, EarlyView.An advanced microneedle patch integrating niobium carbide nanosheets and curcumin is engineered for diabetic wound healing. The system enables dual ROS scavenging and NIR‐enhanced antimicrobial activity, effectively rebalancing the oxidative microenvironment, promoting macrophage repolarization and angiogenesis, and accelerating full‐thickness wound ...
Zhi Zheng +12 more
wiley +1 more source
High-fat diet and streptozotocin in the induction of type 2 diabetes mellitus: a new proposal
Anais da Academia Brasileira de Ciências, 2019 Our objective was to establish a diabetes mellitus type 2 (DM2) model in rats using a high-fat diet and streptozotocin (HF-STZ). Male Wistar rats (240-250g) were divided into a control group (commercial feed), and HF-STZ group, (66.5%-commercial feed, 13.
DIEGO A. DE MAGALHÃES +7 more
doaj +1 more source
The effect of Urtica dioica extract on the number of astrocytes in the dentate gyrus of diabetic rats [PDF]
, 2009 Diabetes mellitus is associated with cerebral alterations in both human and animal models of the disease. These alterations include abnormal expression of hypothalamic neuropeptides and hippocampal astrogliosis.
Afshar, M. +2 more
core
Advanced Materials, EarlyView.The research demonstrates a Mesenchymal Stem Cell‐inspired microneedle platform (MSCi@MN) that addresses chronic diabetic wounds by combining MSC‐derived extracellular nanovesicles (NV)–DNA conjugates in microneedle tips with photothermal MXene in the patch layer.
Chan Ho Moon +21 more
wiley +1 more source