ABSTRACT Objective Despite the availability of effective therapies for Multiple Sclerosis (MS), the unpredictable nature of disease progression and the variability in individual treatment outcomes call for reliable biomarkers. This pilot study aims to investigate the potential of plasma circulating microRNAs (miRNAs) as predictive biomarkers for ...
Fortunata Carbone+19 more
wiley +1 more source
Integrating 3D Printing with Injection Molding for Improved Manufacturing Efficiency. [PDF]
Chval Z, Raz K, da Silva JPAB.
europepmc +1 more source
Factors for Rituximab Refractoriness in AQP4‐IgG+ NMOSD: A Cohort Study
ABSTRACT Objective Neuromyelitis optica spectrum disorder (NMOSD) is a severe autoimmune condition of the central nervous system (CNS), often associated with aquaporin‐4 antibodies (AQP4‐IgG). Rituximab, a CD20+ B‐cell depleting monoclonal antibody, is widely used as first‐line therapy.
Mariano Marrodan+8 more
wiley +1 more source
Mechanical behavior and energy absorption capability of trigonometric function curved rod cell-based lattice structures under compressive loading. [PDF]
Zhang L, Wu J, Zhao Y, Qin Z.
europepmc +1 more source
The Diagnostic Value of Visual Evoked Potentials in Chronic Disorders of Consciousness
ABSTRACT Objective In chronic disorders of consciousness (DOCs), the distinction between vegetative state/unresponsive wakefulness syndrome (VS/UWS) and minimally conscious state (MCS) is as crucial as it is challenging. Evoked potentials (EPs) and event‐related potentials (ERPs) are helpful, but some limitations prevent their consistent use in the ...
Letizia Clementi+14 more
wiley +1 more source
Experimental study on mechanical properties of composite materials of concrete and foamed cement under uniaxial compression. [PDF]
Cao Y+6 more
europepmc +1 more source
ABSTRACT Introduction The kappa‐free light chain (κ‐FLC) index is known to be highly sensitive and specific for diagnosing multiple sclerosis (MS), while little is understood about lambda (λ)‐FLC. This study assessed the κ‐FLC and λ‐FLC indices in autoimmune glial fibrillary acidic protein (GFAP) astrocytopathy.
Michael Levraut+11 more
wiley +1 more source
Mechanical Tensile Response of Ni-Graphene Nanocomposites in Hydrogen-Irradiation-Coupled Environments Using Molecular Dynamics Simulations. [PDF]
Liu T, Yuan X, Huang H.
europepmc +1 more source
Stage‐Dependent Inhibitory Connectivity in Striatal‐Motor Circuit in Huntington's Disease
ABSTRACT Background Elucidating dysfunctional connectivity patterns among key brain regions in Huntington's disease (HD) underlying progression may have implications for developing treatment and therapeutic evaluation. Objective Explore the relationship between abnormal spontaneous resting‐state activity and atrophy in HD‐specific brain regions and ...
Yinghua Jing+4 more
wiley +1 more source
Process Parameters Optimization and Mechanical Properties of Additively Manufactured Ankle-Foot Orthoses Based on Polypropylene. [PDF]
Swesi S, Yousfi M, Tardif N, Banoune A.
europepmc +1 more source