Long-range correlations and fractal dynamics in C. elegans: changes with aging and stress
, 2017 Reduced motor control is one of the most frequent features associated with aging and disease. Nonlinear and fractal analyses have proved to be useful in investigating human physiological alterations with age and disease.
Alves, Luiz G. A. +5 more
core +1 more source
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
FEBS Letters, EarlyView.Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
Evaluating cognitive bias in clinical ethics supports: a scoping review
BMC Medical EthicsBackground A variety of cognitive biases are known to compromise ethical deliberation and decision-making processes. However, little is known about their role in clinical ethics supports (CES).
Louise Giaume +4 more
doaj +1 more source
Identification of Resilient Individuals and Those at Risk for Performance Deficits under Stress
Frontiers in Neuroscience, 2015 Human task performance is affected by exposure to physiological and psychological stress. The ability to measure the physiological response to stressors and correlate that to task performance could be used to identify resilient individuals or those at ...
Brent eWinslow +4 more
doaj +1 more source
Incidence of ill-health related job loss and related social and occupational factors. The “unfit for the job” study: a one-year follow-up study of 51,132 workers [PDF]
PeerJ, 2018 Objective The analysis of ill-health related job loss may be a relevant indicator for the prioritization of actions in the workplace or in the field of public health, as well as a target for health promotion.
Francois-Xavier Lesage +4 more
doaj +2 more sources
Evaluation of Argentine wild sunflower biotypes for drought stress during reproductive stage [PDF]
, 2012 As in several regions where sunflower production has moved to areas with limiting water availability, the search for water-stress tolerant genotypes has been intensified. Helianthus annuus ssp. annuus L.
Cantamutto, Miguel Ángel +3 more
core +1 more source
FEBS Letters, EarlyView.This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Prosocial Behavior as a Stress Moderator: The Physiological and Psychological Components [PDF]
, 2018 Stress is a major part of everyday life for the majority of people, especially college students. Stress has a physiological response and serves an important purpose in the body.
Vannelli, Jessica
core +1 more source
Time after time – circadian clocks through the lens of oscillator theory
FEBS Letters, EarlyView.Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source