Results 61 to 70 of about 483,350 (311)
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
FEBS Open Bio, EarlyView.dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon +6 more
wiley +1 more source
Investigations of the Compressive Behaviour of Veneer in Thickness Direction
Drvna Industrija, 2012 Compression tests were conducted with veneers in the thickness direction. Thereby differences between the stress-strain curves of veneers and other known stress-strain curves were observed.
Beate Buchelt +2 more
doaj
Properties evolution of flax/epoxy composites under fatigue loading [PDF]
, 2014 The tension–tension fatigue behaviour of flax fibre reinforced epoxy matrix composites have been investigated for specimens having [0]12, [90]12, [0/90]3S and [±45]3S lay-ups.
GNING, Papa-Birame +2 more
core +7 more sources
FEBS Open Bio, EarlyView.A tri‐culture of iPSC‐derived neurons, astrocytes, and microglia treated with ferroptosis inducers as an Induced ferroptosis model was characterized by scRNA‐seq, cell survival, and cytokine release assays. This analysis revealed diverse microglial transcriptomic changes, indicating that the system captures key aspects of the complex cellular ...
Hongmei Lisa Li +6 more
wiley +1 more source
Stress Relaxation Behaviour and Creep Constitutive Equations of SA302Gr.C Low-Alloy Steel
High Temperature Materials and Processes, 2018 In order to study the stress relaxation behaviour of SA302Gr.C low-alloy steel, the stress relaxation experiments were performed at the temperatures of 400, 500 and 620 °C with the constant strain of 0.5 %.
Shen Wenfei +4 more
doaj +1 more source
Modeling of critical strain for dynamic recrystallization of niobium microalloyed steels
Materials Research Express, 2022 The critical strain for dynamic recrystallization (DRX) is most important in designing rolling schedules for the refinement of grain size by boundary-induced transformation mechanisms. Modeling of the critical strain for DRX from the stress-strain curves
Jun Xing +4 more
doaj +1 more source
Revisiting the method to obtain the mechanical properties of hydrided fuel cladding in the hoop direction [PDF]
, 2012 The method reported in the literature to calculate the stress–strain curve of nuclear fuel cladding from ring tensile test is revisited in this paper and a new alternative is presented.
A. Valiente +10 more
core +2 more sources
Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control
FEBS Open Bio, EarlyView.Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada +5 more
wiley +1 more source
Stress-strain response and microstructural evolution of a FeMnCAl TWIP steel during tension-compression tests [PDF]
, 2016 © 2016. The stress-strain response of a Fe-17.5Mn-0.7C-2Al TWIP steel during cyclic loading has been investigated by means of tension-compression tests within the strain limits of ±2%, ±5% and ±10%. In addition, the microstructural evolution during the ±
Benito Páramo, José Antonio +3 more
core +2 more sources