Results 71 to 80 of about 1,454,667 (331)

Experimental study on electro-mechanical response characteristics of PZT5H piezoelectric ceramics under impact loading

Journal of Asian Ceramic Societies, 2021
Using Servo Testing Machine and Split Hopkinson Pressure Bar measurement device, an experimental study on the electro-mechanical characteristics of PZT5H piezoelectric ceramics under quasi-static and impact loading are carried out.
Zhengchun Xie, Xianyang Xu
doaj   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Development and analysis method of single element strain gage for stress intensity factor analysis in crack opening mode (Verification of analysis accuracy by simulated crack)

Nihon Kikai Gakkai ronbunshu, 2022
A dedicated strain gage has been developed to measure the stress intensity factor of cracks. Conventional strain gages dedicated to stress intensity factor analysis have been made by combining multiple elements into a single gage. Therefore, it took time
Shigeru KUROSAKI, Jyo SHIMURA, Syusaku YAMAJI, Mitsutaka KANEHIRA, Takeshi SHIMURA   +4 more
doaj   +1 more source

Measurement of local creep properties in stainless steel welds [PDF]

, 2012
A high temperature measurement system for creep deformation based on the digital image correlation (DIC) technique is described. The new system is applied to study the behaviour of a multi-pass welded joint in a high temperature tensile test and a load ...
Bouchard, J., Gungor, S., Sakanashi, Y.
core  

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Preliminary Results of Stress Measurement Using Drill Cores of TCDP Hole-A: an Application of Anelastic Strain Recovery Method to Three-Dimensional In-Situ Stress Determination

Terrestrial, Atmospheric and Oceanic Sciences, 2007
In order to understand the feature of rock stress change at different depths above, within, and beneath the Chelungpu fault after the Chi-Chi earthquake, we employed a core-based stress measurement method, anelastic strain recovery (ASR) technique to ...
Weiren Lin En-Chao Yeh1, Hisao Ito, Tetsuro Hirono, Wonn Soh, Chien-Ying Wang, Kuo-Fong Ma, Jih-Hao Hung, and Sheng-Rong Song   +7 more
doaj   +2 more sources

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source

Shock Wave Pressure Measurement and Calibration Method Based on Bar Pressure Sensor

Sensors
In order to correctly measure the shock wave pressure generated by a near-field explosion, and while considering the limitations of the measurement and calibration method of the current bar pressure sensor, an improved shock wave pressure measurement ...
Yong-Xiang Shi, Ying-Cheng Peng, Yuan-Ding Xing, Xue-Jie Jiao, Xiao-Fei Huang, Ze-Qun Ba   +5 more
doaj   +1 more source

Microglial dynamics and ferroptosis induction in human iPSC‐derived neuron–astrocyte–microglia tri‐cultures

FEBS Open Bio, EarlyView.
A tri‐culture of iPSC‐derived neurons, astrocytes, and microglia treated with ferroptosis inducers as an Induced ferroptosis model was characterized by scRNA‐seq, cell survival, and cytokine release assays. This analysis revealed diverse microglial transcriptomic changes, indicating that the system captures key aspects of the complex cellular ...
Hongmei Lisa Li, Hiroko Ohmiya, Sou Sakamoto, Masato Yugami, Akiko Oki, Makoto Furusawa, Yan Ling   +6 more
wiley   +1 more source