Post-fatigue fracture load, stress concentration and mechanical properties of feldspathic, leucite- and lithium disilicate-reinforced glass ceramics. [PDF]
Heliyon, 2023 Capobianco V +8 more
europepmc +1 more source
Molecular Oncology, EarlyView.The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola +12 more
wiley +1 more source
Microstructure, Fatigue Properties and Stress Concentration Analysis of 6005 Aluminum Alloy MIG Welded Lap Joint. [PDF]
Materials (Basel), 2022 Li Y, Yang S, Peng Z, Wang Z, Gao Z.
europepmc +1 more source
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
Molecular Oncology, EarlyView.We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source
Effect of Antirotational Two-Piece Titanium Base on the Vertical Misfit, Fatigue Behavior, Stress Concentration, and Fracture Load of Implant-Supported Zirconia Crowns. [PDF]
Materials (Basel), 2023 Adolfi D +4 more
europepmc +1 more source
Risk, Concentration and Market Power in the Banking Industry: Evidence from the Colombian System (1997-2006) [PDF]
This paper examines the relationship between risk, concentration and the exercise of market power by banking institutions. We use monthly balance-sheet and interest rate data for the Colombian banking system from 1997 to 2006. The evidence shows that, in
Carlos Hernández +2 more
core
Molecular Oncology, EarlyView.The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source
Stress Concentration Factors in Excavation Repairs of Surface Defects in Forgings and Castings. [PDF]
Materials (Basel), 2022 Rebora A, Torre G, Vernassa G.
europepmc +1 more source
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Stress Concentration Analysis of the Corroded Steel Plate Strengthened with Carbon Fiber Reinforced Polymer (CFRP) Plates. [PDF]
Polymers (Basel), 2022 Li A, Wang H, Li H, Kong D, Xu S.
europepmc +1 more source