Results 91 to 100 of about 371,044 (285)

Reliability approach to rotating-component design [PDF]

A probabilistic methodology for designing rotating mechanical components using reliability to relate stress to strength is explained. The experimental test machines and data obtained for steel to verify this methodology are described. A sample mechanical
Kececioglu, D. B., Lalli, V. R.
core   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Elasticidade, plasticidade, histerese... e ondas

Revista Brasileira de Ensino de Física
Neste artigo é descrito um experimento que permite estudar as propriedades mecânicas de fios sob tração. O experimento requer um monocórdio, no qual o fio é esticado e tangido, um microcomputador com placa de som e um software para análise espectral do ...
Luiz André Mützenberg, Eliane Angela Veit, Fernando Lang da Silveira   +2 more
doaj  

Macroscopic fe-simulation of residual stresses in thermo-mechanically processed steels considering phase transformation effects [PDF]

, 2019
Residual stresses are an important issue as they affect both the manufacturing processes as well as the performance of the final parts. Taking into account the whole process chain of hot forming, the integrated heat treatment provided by a defined ...
Behrens, B. A., Chugreev, A., Kock, C.
core  

On $C_{J}$ and $C_{T}$ in Conformal QED

, 2016
QED with a large number $N$ of massless fermionic degrees of freedom has a conformal phase in a range of space-time dimensions. We use a large $N$ diagrammatic approach to calculate the leading corrections to $C_T$, the coefficient of the two-point ...
Giombi, Simone, Klebanov, Igor R., Tarnopolsky, Grigory   +2 more
core   +1 more source

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

Molecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir, Lukasz Arcimowicz, Lucia Martinkova, Vaclav Hrabal, Filip Zavadil Kokas, Tomas Henek, Martina Kucerikova, Ondrej Bonczek, Pavlina Zatloukalova, Lenka Hernychova, Philip J. Coates, Borivoj Vojtesek, David P. Lane   +12 more
wiley   +1 more source

Critical dynamics of an isothermal compressible non-ideal fluid

, 2012
A pure fluid at its critical point shows a dramatic slow-down in its dynamics, due to a divergence of the order-parameter susceptibility and the coefficient of heat transport.
A. Onuki, Fathollah Varnik, G. F. Mazenko, G. L. Gaines Jr., H. E. Stanley, J. K. Bhattacharjee, J. Lowengrub, J. P. Boon, J. V. Sengers, J.-P. Hansen, K. Kawasaki, L. D. Landau, Markus Gross, O. G. Mouritsen, P. Kopietz, P. M. Chaikin, S. P. Das, S.-K. Ma, U. Frisch   +18 more
core   +1 more source

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

Molecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He, Chiara Testini, Neda Hekmati, Altea Bonello, Aglaia Schiza, Emmanuel Nwadozi, Mia Phillipson, Carina Strell, Michael Welsh   +8 more
wiley   +1 more source

Experimental and theoretical research on reinforced lightweight concrete flexural elements / Armuotojo lengvojo betono lenkiamųjų elementų eksperimentiniai ir teoriniai tyrimai

Mokslas: Lietuvos Ateitis, 2014
The paper deals with analysis of structural lightweight concrete. New lightweight concrete mixture made with expanded clay aggregate has been proposed and applied for experimental rein-forced concrete beams.
Deividas Rumšys, Darius Bačinskas, Edmundas Spudulis, Eugenijus Gudonis, Aleksandr Sokolov   +4 more
doaj   +1 more source

On $C_J$ and $C_T$ in the Gross-Neveu and $O(N)$ Models

, 2016
We apply large $N$ diagrammatic techniques for theories with double-trace interactions to the leading corrections to $C_J$, the coefficient of a conserved current two-point function, and $C_T$, the coefficient of the stress-energy tensor two-point ...
Diab, Kenan, Fei, Lin, Giombi, Simone, Klebanov, Igor R., Tarnopolsky, Grigory   +4 more
core   +1 more source