Results 51 to 60 of about 371,044 (285)

Sensitivity Analysis of Steel Box-Section Girders. [PDF]

, 2013
The paper deals with the load–carrying capacity stochastic variance based sensitivity analysis of thin–walled box–section girder subjected to pure bending. The lower– and uppe-r-bound load–capacity estimation is performed. The methodology is based on the
Kotełko, Maria, Lis, Paweł
core  

First-principles study of epitaxial strain in perovskites

, 2005
Using an extension of a first-principles method developed by King-Smith and Vanderbilt [Phys. Rev. B {\bf 49}, 5828 (1994)], we investigate the effects of in-plane epitaxial strain on the ground-state structure and polarization of eight perovskite oxides:
D. Vanderbilt, David Vanderbilt, J. B. Neaton, J. S. Speck, Karin M. Rabe, M. E. Lines, Oswaldo Diéguez   +6 more
core   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

The triangular stress diagram; a graphical representation of crustal stress measurements [PDF]

Professional Paper, 1984
A new graphical method is introduced that facilitates the representation and interpretation of the generally anisotropic in situ states-ofstress measured in rocks. The purpose of the method is to clearly and easily display these stress states, each measured in terms of three values, in two-dimensional space; this is done by projecting three-dimensional
openaire   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

FEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo, Carolin Ector, Hanspeter Herzel   +2 more
wiley   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

Improvement of the mathematical model of the diagram of deformation of the compressed composite steel and concrete structures

MATEC Web of Conferences, 2017
The mathematical model of the stress-strain ratio of compressed concrete at elevated temperatures for composite structures described in Eurocode EN 1994-1-2:2005 Eurocode 4 divided in two stages: Stage 1 - represents the ascending branch and is defined ...
Fomin Stanislav, Izbash Yuriy, Plakhotnikova Iryna, Butenko Serhii, Shemet Ruslan   +4 more
doaj   +1 more source

Network stress: A wiring diagram of whole stress genes

Horticulture Research
Abstracts Stress sensitivity and tolerance are the consequences of coordinated regulation by multiple genes. Existing genetic tools can identify key genes that mediate metabolic and physiological processes sensing and perceiving stresses.
Yu Wang, Rongling Wu
openaire   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Determination of Limiting Deformations at Testing Cylindrical Samples for Tension

Проблеми трибології
This paper proposes a method for calculating limiting deformations under conditions of localized deformation during tensile testing. The method for calculating limiting deformations was used to construct plasticity diagrams under conditions of strain ...
I. Iu. Kyrytsya, O.V. Petrov, I.V. Vishtak, S.I. Sukhorukov   +3 more
doaj   +1 more source