Results 61 to 70 of about 371,044 (285)

Couple-Stress Fluid Improves Dynamic Response of Gear-Pair System Supported by Journal Bearings

open access: yesJournal of Applied Mathematics, 2012
A systematic analysis of the dynamic behavior of a gear-bearing system with nonlinear suspension, couple-stress fluid flow effect, nonlinear oil-film force, and nonlinear gear mesh force is performed in the present study. The dynamic orbits of the system
Cai-Wan Chang-Jian   +2 more
doaj   +1 more source

The Effect of Negative-Energy Shells on the Schwarzschild Black Hole [PDF]

open access: yes, 2009
We construct Penrose diagrams for Schwarzschild spacetimes joined by massless shells of matter, in the process correcting minor flaws in the similar diagrams drawn by Dray and 't Hooft, and confirming their result that such shells generate a horizon ...
B. Carter   +15 more
core   +3 more sources

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

open access: yesMolecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero   +8 more
wiley   +1 more source

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

open access: yesMolecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou   +5 more
wiley   +1 more source

Interaction Diagrams of Short Rectangular RPC Columns Under Combined Axial Load Plus Uniaxial Bending

open access: yesJournal of Engineering and Sustainable Development, 2014
Reactive Powder Concrete (RPC) represents one of the latest developments in concrete technology. The material and mechanical characteristics of RPC are significantly greater than the current ordinary concretes types classified as high-performance ...
Hisham Al-Hassani, Samer Hannawayya
doaj  

Two-loop MHV form factors from the periodic Wilson loop

open access: yesJournal of High Energy Physics
We discuss how to compute maximal-helicity-violating (MHV) form factors for the chiral part of the stress-tensor supermultiplet from periodic light-like polygon Wilson loops in planar N $$ \mathcal{N} $$ = 4 super Yang-Mills theory beyond the one-loop ...
Zhenjie Li
doaj   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham   +21 more
wiley   +1 more source

Deformation-strength model application at the determining of stress-strain state of reinforced concrete structures

open access: yesTrudy Odesskogo Politehničeskogo Universiteta, 2017
The work considers the possibility and expediency of deformation-strength model applica-tion in the study of stress-strain state of reinforced concrete structures.
Karpiuk V. M.   +3 more
doaj   +1 more source

Strain-induced energy band gap opening in two-dimensional bilayered silicon film

open access: yes, 2015
This work presents a theoretical study of the structural and electronic properties of bilayered silicon films under in-plane biaxial strain/stress using density functional theory.
Ji, Zhonghang   +3 more
core   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

open access: yesMolecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan   +9 more
wiley   +1 more source

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