Results 91 to 100 of about 967,721 (269)
Dizhen xuebao利用双差定位法对2010年8月1日至2014年12月31日福建仙游地区中国地震台网中心记录到的地震群进行重定位，并采用P波初动的方法求解出该震群的159个震源机制解，显示该震群的震源机制解结果与背景构造应力场表现明显不一致。为了进一步探究差异性存在的原因，将得到的震群震源机制解结果分区域和分深度求解应力场，结果显示：金钟水库的东南部附近应力方向更远离背景构造应力方向，并且应力形因子小于0.5，中间轴呈现为拉张应力；随着深度的增加，应力场的方向也更接近背景构造应力场的方向。此外 ...
Hailin Yu +4 more
doaj +1 more source
Directed evolution of enzymes at the crossroads of tradition and innovation
FEBS Open Bio, EarlyView.An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova +2 more
wiley +1 more source
Numerical Simulation of Stress Field in Laser Cladded Gate of Flat Gate Valve
Shiyou jixie, 2016 As a key member of gate valve, the abrasion and corrosion of the gate can severely hamper the application of flat gate valve in the oil industry.Based on thermal elastoplastic theory, laser cladding of the gate with Ni-based alloy was simulated by means ...
Cai Chunbo +3 more
doaj
Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1
FEBS Open Bio, EarlyView.The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay +2 more
wiley +1 more source
Design method and application of temporary plugging by fiber and diverting acid fracturing
Youqicang pingjia yu kaifa, 2019 In order to solve the problem of quantitative design of fiber in fiber temporary plugging and diverting acid fracturing, a total stress field model considering the initial artificial fracture, adjacent well artificial fracture, pore pressure change ...
Zhifeng LUO +5 more
doaj
FEBS Open Bio, EarlyView.TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose +9 more
wiley +1 more source
Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes
FEBS Open Bio, EarlyView.Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard +12 more
wiley +1 more source
FEBS Open Bio, EarlyView.Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya +2 more
wiley +1 more source
How phagocytic cells kill bacteria: Lessons from a professional killer
FEBS Open Bio, EarlyView.How phagocytic cells ingest and kill bacteria has been studied for more than a century, but many questions remain unanswered. The study of the amoeba Dictyostelium discoideum brings new answers, and new questions. Professional phagocytic cells such as neutrophils and macrophages, as well as free‐living soil amoebae like Dictyostelium discoideum, employ
Otmane Lamrabet, Pierre Cosson
wiley +1 more source