Results 101 to 110 of about 10,570,709 (289)

Numerical Simulation of Stress Field in Laser Cladded Gate of Flat Gate Valve

open access: yesShiyou jixie, 2016
As a key member of gate valve, the abrasion and corrosion of the gate can severely hamper the application of flat gate valve in the oil industry.Based on thermal elastoplastic theory, laser cladding of the gate with Ni-based alloy was simulated by means ...
Cai Chunbo   +3 more
doaj  

Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer

open access: yesMolecular Oncology, EarlyView.
Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba   +5 more
wiley   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

open access: yesFEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj   +3 more
wiley   +1 more source

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

open access: yesFEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour   +2 more
wiley   +1 more source

福建仙游震群的应力场及其成因分析

open access: yesDizhen xuebao
利用双差定位法对2010年8月1日至2014年12月31日福建仙游地区中国地震台网中心记录到的地震群进行重定位,并采用P波初动的方法求解出该震群的159个震源机制解,显示该震群的震源机制解结果与背景构造应力场表现明显不一致。为了进一步探究差异性存在的原因,将得到的震群震源机制解结果分区域和分深度求解应力场,结果显示:金钟水库的东南部附近应力方向更远离背景构造应力方向,并且应力形因子小于0.5,中间轴呈现为拉张应力;随着深度的增加,应力场的方向也更接近背景构造应力场的方向。此外 ...
Hailin Yu   +4 more
doaj   +1 more source

Versatile vector tools for efficient protein screening across multiple expression systems

open access: yesFEBS Open Bio, EarlyView.
A unified vector toolkit enables rapid protein expression screening across E. coli, insect, and mammalian cells. A single primer pair amplifies the target gene, which is inserted into any vector via a standardized interface. This streamlined workflow eliminates repeated cloning steps, accelerating the identification of optimal expression conditions for
Zhimin Zhu   +5 more
wiley   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

open access: yesFEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová   +2 more
wiley   +1 more source

As a researcher engaging in the field of oxidative stress

open access: yesJournal of Clinical Biochemistry and Nutrition, 2011
The awful earthquake that attacked Northeast part of Japan on 11th March 2011 caused a massive tsunami to surge against the coastal place at Kanto and Tohoku area. Besides, it ran over the serious damage of the Fukushima Daiichi Nuclear Power Plant located at the coastal place of north Kanto area.
openaire   +3 more sources

Posttraumatic stress disorder : scientific and professional dimensions /

open access: yes
This comprehensive overview of research and clinical practice in PTSD includes new insights into assessment with regard to DSM-5 and ICD-11, discussion of ongoing controversies in the field as to what constitutes safe and effective care, and new research
Ford, Julian D.,author.   +4 more
core  

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