Results 81 to 90 of about 10,570,709 (289)

A parametric study of laser spot size and coverage on the laser shock peening induced residual stress in thin aluminium samples

The Journal of Engineering, 2015
Laser Shock Peening is a fatigue enhancement treatment using laser energy to induce compressive Residual Stresses (RS) in the outer layers of metallic components.
M. Sticchi, P. Staron, Y. Sano, M. Meixer, M. Klaus, J. Rebelo-Kornmeier, N. Huber, N. Kashaev   +7 more
doaj   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Regional stress field of the Indian Plate

Geophysical Research Letters, 1985
We have calculated the regional stress field in the Indian plate, implementing dependence of slab pull and ridge push on the age of the oceanic lithosphere in the finite element procedure. The high level of the calculated stress field (order of a few kbar) and the dominance of compression in the plate are consequences of the unique dynamic situation of
Cloetingh, Sierd, Wortel, Rinus
openaire   +2 more sources

Numerical study of the influence of seepage force on the stress field around a vertical wellbore

Engineering Applications of Computational Fluid Mechanics, 2020
Fluid seepage into rock pores not only generates poroelastic stress but also exerts seepage force on the rock skeleton. However, since the mechanism of the effect of seepage force on the stress field around the wellbore is not clear, conventional methods
Desheng Zhou, Haiyang Wang, ZeXuan He, Yafei Liu, Shun Liu, Xianlin Ma, Wenbin Cai, Jinqing Bao   +7 more
doaj   +1 more source

Cancer‐associated mutations in endometriosis reframe a benign disease through molecular oncology

Molecular Oncology, EarlyView.
This review aims to comprehensively analyse cancer‐associated somatic mutations (CAMs) present in endometriotic lesions, emphasizing their biological roles, spatial distribution and implications for translational applications in medicine. By contextualizing a benign state within a genomic framework, this analysis seeks to establish its value as a ...
Clarissa Mujacic, Maria Concetta Vitale, Rita Siino, Emilia Di Giovanni, Carla Ferrante Bannera, Enrico Di Marco, Andrea Gottardo, Tancredi Didier Bazan Russo, Nadia Barraco, Alessandro Perez, Valerio Gristina, Antonio Galvano, Giuseppe Badalamenti, Antonio Russo, Viviana Bazan, Lorena Incorvaia   +15 more
wiley   +1 more source

Regularity of three fields evolution of hydraulic fracturing process in coal seam

Gong-kuang zidonghua, 2016
Numerical simulation was conducted for hydraulic fracturing process in coal seam according to solid-liquid coupling equations and Mohr-Coulomb principle.
XU Zhaoyong, SONG Dazhao, QIU Liming, WANG Enyuan, MA Yafei, HE Junjiang   +5 more
doaj   +1 more source

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

Determining the stress field in active volcanoes using focal mechanisms

Frontiers in Earth Science, 2016
Stress inversion of seismological datasets became an essential tool to retrieve the stress field of active tectonics and volcanic areas. In particular, in volcanic areas, it is able to put constrains on volcano-tectonics and in general in a better ...
Bruno Massa, Bruno Massa, Luca D'Auria, Luca D'Auria, Elena Cristiano, Ada De Matteo   +5 more
doaj   +1 more source

Effect of drought stress on yield, proline and chlorophyll contents in three chickpea cultivars [PDF]

, 2010
Drought stress is one of the major abiotic stresses in agriculture worldwide. This study was carried out to investigate the effect of drought stress on proline content, chlorophyll content, photosynthesis and transpiration, stomatal conductance and yield
Siosemardeh, A., Mafakheri, A., Struik, P.C., Bahramnejad, B., Sohrabi, Y.   +4 more
core  

Castration‐resistant prostate cancer cells are addicted to the high activity of cyclin‐dependent kinase 2

Molecular Oncology, EarlyView.
We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee, Alessia Marin, Shivani Yalala, Harri M. Itkonen   +3 more
wiley   +1 more source