Results 111 to 120 of about 4,657,064 (329)

Mechanism and effect of stress granule formation in cancer and its potential roles in breast cancer therapy

Genes and Diseases, 2021
Stress granules are non-membranous cytoplasmic foci induced by various stress conditions. It is a protective strategy used by cells to suppress overall translation during stress. In cancer cells, it was thought that the formation of stress granules could
Taobo Hu, W. Hou, E. Xiao, M. Long
semanticscholar   +1 more source

Role of Chikungunya nsP3 in Regulating G3BP1 Activity, Stress Granule Formation and Drug Efficacy

, 2021
BACKGROUND: Ras-GTPase activating protein SH3-domain-binding proteins (G3BP) are a small family of RNA-binding proteins implicated in regulating gene expression.
Kennedy, Derek, Willis, Charlene, Alam, Umber, Lu, Xue   +3 more
core   +1 more source

Long non-coding RNA SNHG8 drives stress granule formation in tauopathies [PDF]

, 2023
Tauopathies are a heterogenous group of neurodegenerative disorders characterized by tau aggregation in the brain. In a subset of tauopathies, rare mutations in the MAPT gene, which encodes the tau protein, are sufficient to cause disease; however, the ...
Bhagat, Reshma, Eteleeb, Abdallah M, Renganathan, Arun, Spina, Salvatore, Martinez, Rita, Minaya, Miguel A, Grinberg, Lea T, Marsh, Jacob, Mehra, Muneshwar, Karch, Celeste M, Seeley, William W, Nana, Alissa L   +11 more
core   +1 more source

Powder Optimization Strategies for Binder Jetting Printing of BaTiO3 and Ba0,6Sr0,4TiO3 Ceramics

Advanced Engineering Materials, EarlyView.
Powder optimization is investigated to enable binder jetting of BaTiO3 and Ba0.6Sr0.4TiO3 ferroelectric ceramics. The antagonistic relationship between flowability and binder compatibility is addressed through binder impregnation of granulated powders and fumed silica addition to fine powders.
Fanny Pruvost, Lionel Presmanes, Soléna Colin, Marie Vidal, Sophie Guillemet‐Fritsch   +4 more
wiley   +1 more source

Stress granule transcription [PDF]

Science, 2018
Molecular Biology When translation initiation is stalled under stress, nontranslating messenger ribonucleoproteins form insoluble assemblies called stress granules (SGs) in the cytosol. Namkoong et al. sequenced all transcripts from purified SGs. They found that although translation of most transcripts is inhibited, only a subset of transcripts form ...
openaire   +1 more source

Stress granules dynamics: benefits in cancer

BMB Reports, 2022
Stress granules (SGs) are stress-induced subcellular compartments, which carry out a particular function to cope with stress. These granules protect cells from stress-related damage and cell death through dynamic sequestration of numerous ribonucleoproteins (RNPs) and signaling proteins, thereby promoting cell survival under both physiological and ...
Jeong In Lee, Sim Namkoong
openaire   +2 more sources

Incorporation of Selenium into Sol–Gel‐Derived Bioactive Glass: Influence on Glass Structure, Bioactivity, and its Selective Cytotoxicity

Advanced Engineering Materials, EarlyView.
Selenium was incorporated into a sol–gel‐derived bioactive glass to enable sustained therapeutic ion release. The selenium‐containing glass preserved bioactivity while selectively inducing cytotoxicity in osteosarcoma cells and maintaining osteoblastic viability.
Breno Rocha Barrioni, Thalita Marcolan Valverde, Talita Martins, Guilherme Mattos Jardim Costa, Alfredo Miranda de Goes, Marcello Rosa Dumont, Eduardo Henrique Martins Nunes, Marivalda de Magalhães Pereira   +7 more
wiley   +1 more source

TIA1 mutations in amyotrophic lateral sclerosis and frontotemporal dementia promote phase separation and alter stress granule dynamics

Neuron, 2017
SUMMARY Amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) are age-related neurodegenerative disorders with shared genetic etiologies and overlapping clinical and pathological features.
I. Mackenzie, Alexandra M. Nicholson, Mohona Sarkar, James Messing, M. Purice, Cyril Pottier, Kavya Annu, M. Baker, R. B. Perkerson, Aishe Kurti, Billie J. Matchett, Tanja Mittag, Jamshid Temirov, G. Hsiung, C. Krieger, M. Murray, M. Kato, J. Fryer, L. Petrucelli, L. Zinman, S. Weintraub, M. Mesulam, J. Keith, S. Zivkovic, V. Hirsch-Reinshagen, R. Roos, S. Züchner, N. Graff-Radford, R. Petersen, R. Caselli, Z. Wszolek, E. Finger, C. Lippa, D. Lacomis, H. Stewart, D. Dickson, Hong-Joo Kim, E. Rogaeva, E. Bigio, K. Boylan, J. Taylor, R. Rademakers   +41 more
semanticscholar   +1 more source

The Orb6-Sts5 Axis Regulates Stress Granule Formation and Heat Stress Response in Fission Yeast

, 2021
The NDR/LATS family kinases are a subclass of the AGC serine/threonine kinases which are important for morphogenesis and cell growth control. Using the model organism Schizosaccharomyces pombe, we previously reported that the NDR/LATS kinase Orb6 ...
Chen, Chuan, Verde, Fulvia, Nuñez, Illyce, Tams, Robert, Haller, Patrick Roman   +4 more
core   +1 more source

Laser‐Induced Graphene from Waste Almond Shells

Advanced Functional Materials, EarlyView.
Almond shells, an abundant agricultural by‐product, are repurposed to create a fully bioderived almond shell/chitosan composite (ASC) degradable in soil. ASC is converted into laser‐induced graphene (LIG) by laser scribing and proposed as a substrate for transient electronics.
Yulia Steksova, Anna Chiara Bressi, Marina Galliani, Attilio Marino, Gianni Ciofani, Eduardo Machado‐Charry, Hilda Gomez Bernal, Alessandra Francini, Luca Sebastiani, Francesco Greco   +9 more
wiley   +1 more source