Results 131 to 140 of about 4,657,064 (329)

Mixed‐Metal Promotion in a Manganese‐Molybdenum Oxynitride as Catalyst to Integrate C─C and C─N Coupling Reactions for the Direct Synthesis of Acetonitrile from Syngas and Ammonia

Advanced Materials, EarlyView.
Transition metal oxy/carbo‐nitrides show great promise as catalysts for sustainable processes. A Mn‐Mo mixed‐metal oxynitride attains remarkable performance for the direct synthesis of acetonitrile, an important commodity chemical, via sequential C─N and C─C coupling from syngas (C1) and ammonia (N1) feedstocks.
M. Elena Martínez‐Monje, Wilson Henao, Tania Rodenas, Patricia Concepción, Virginia Pérez Dieste, Alexander Missyul, Giovanni Agostini, Gonzalo Prieto   +7 more
wiley   +1 more source

NS1 binding protein regulates stress granule dynamics and clearance by inhibiting p62 ubiquitination

Nature Communications
The NS1 binding protein, known for interacting with the influenza A virus protein, is involved in RNA processing, cancer, and nerve cell growth regulation. However, its role in stress response independent of viral infections remains unclear.
Pureum Jeon, Hyun-Ji Ham, Haneul Choi, Semin Park, Jae-Woo Jang, Sang-Won Park, Dong-Hyung Cho, Hyun-Jeong Lee, Hyun Kyu Song, Masaaki Komatsu, Dohyun Han, Deok-Jin Jang, Jin-A Lee   +12 more
doaj   +1 more source

Regulation of adult-born and mature neurons in stress response and antidepressant action in the dentate gyrus of the hippocampus

Neuroscience Research
The dentate gyrus (DG) of the hippocampus has been implicated in the regulation of stress responses, and in the pathophysiology and treatment of depression.
Eri Segi-Nishida, Kanzo Suzuki
doaj   +1 more source

Study on the critical stress threshold of weakly cemented sandstone damage based on the renormalization group method

International Journal of Coal Science & Technology, 2020
During the microstructural analysis of weakly cemented sandstone, the granule components and ductile structural parts of the sandstone are typically generalized. Considering the contact between granules in the microstructure of weakly cemented sandstone,
Zhaoyang Song, Hongguang Ji, Zhiqiang Liu, Lihui Sun   +3 more
doaj   +1 more source

Differentiated cytoplasmic granule formation in quiescent and non-quiescent cells upon chronological aging [PDF]

, 2016
Stationary phase cultures represent a complicated cell population comprising at least two different cell types, quiescent (Q) and non-quiescent (NQ) cells. Q and NQ cells have different lifespans and cell physiologies.
Kuo-Yu Cheng, Jung-Chi Chao, Jun-Yi Leu, Hsin-Yi Lee   +3 more
core   +1 more source

Oppositely Charged Single Enzyme Nanogels Form Versatile Coacervates for Efficient Enzyme Cascade Catalysis

Advanced Materials, EarlyView.
Oppositely charged single enzyme nanogels (SENs) phase‐separate into bi‐enzymatic coacervate microdroplets, acting as both scaffold and functional units. By tuning SEN ratios, these coacervates create specific microenvironments that enable selective small‐molecule enrichment and efficient intermediate diffusion.
Andoni Rodriguez‐Abetxuko, Nadia A. Erkamp, Neshat Moslehi, Yannick H. A. Leurs, Lars Paffen, Işil Yeşil Gür, Jana Stojanović, Hugo Brasselet, Laura van der Weel, Ulf Hanefeld, Ilja K. Voets, Jan C. M. van Hest   +11 more
wiley   +1 more source

Modulus‐Switchable Miniature Robots for Biomedical Applications: A Review

Advanced Robotics Research, EarlyView.
Materials, robot designs, proof‐of‐concept functions, and biomedical applications of modulus‐switchable miniature robots. Miniature soft robots have shown great potential in biomedical applications due to their excellent controllability and suitable mechanical properties in biological environments.
Chunyun Wei, Yibin Wang, Jiangfan Yu
wiley   +1 more source

Drug-induced Stress Granule Formation Protects Sensory Hair Cells in Mouse Cochlear Explants During Ototoxicity [PDF]

, 2019
Stress granules regulate RNA translation during cellular stress, a mechanism that is generally presumed to be protective, since stress granule dysregulation caused by mutation or ageing is associated with neurodegenerative disease.
Porco, John A., Gonçalves, Ana Cláudia, Haq, N, Porco, JA, Dawson, Sally J., Gale, Jonathan E., Towers, Emily R., Pelletier, Jerry, Towers, ER, Pelletier, J, Dawson, SJ, Gonçalves, AC, Gale, JE, Haq, Naila   +13 more
core   +1 more source

Unraveling the Molecular Mechanisms Underlying Spontaneous Multipolar Mitosis Through CIN‐seq

Advanced Science, EarlyView.
Multipolar mitosis, a hallmark of chromosomal instability (CIN), drives tumor heterogeneity but is challenging to study in live cells. Using CIN‐seq, a single‐cell multiomics method, we profiled rare CIN events and identified mechanisms associated with viable multipolar mitosis, including PTEN attenuation, Rho GTPase‐driven cytokinesis failure, and ...
Pin‐Rui Su, Ting‐Chun Chou, Maria Teresa López‐Cascales, Junfeng Huang, Tsai‐Ying Chen, Sjoukje van Wieren, Chan Li, Cecile Beerens, Li You, Jelle Storteboom, Miao‐Ping Chien   +10 more
wiley   +1 more source

Stress granule-defective mutants deregulate stress responsive transcripts.

PLoS Genetics, 2014
To reduce expression of gene products not required under stress conditions, eukaryotic cells form large and complex cytoplasmic aggregates of RNA and proteins (stress granules; SGs), where transcripts are kept translationally inert.
Xiaoxue Yang, Yi Shen, Elena Garre, Xinxin Hao, Daniel Krumlinde, Marija Cvijović, Christina Arens, Thomas Nyström, Beidong Liu, Per Sunnerhagen   +9 more
doaj   +1 more source