Results 261 to 270 of about 128,066 (353)

Environmental exposure of the general population to cadmium as a risk factor of the damage to the nervous system: A critical review of current data

open access: yesJournal of Applied Toxicology, Volume 43, Issue 1, Page 66-88, January 2023., 2023
Abstract Nowadays, more and more attention has been focused on the risk of the neurotoxic action of cadmium (Cd) under environmental exposure. Due to the growing incidence of nervous system diseases, including neurodegenerative changes, and suggested involvement of Cd in their aetiopathogenesis, this review aimed to discuss critically this element ...
Agnieszka Ruczaj   +1 more
wiley   +1 more source

Gout and NLRP3 inflammasome biology

open access: yesArthritis &Rheumatology, Accepted Article.
This review describes the three broad stages of acute inflammation in the context of gout: initiation, leucocyte mobilisation, and self‐resolution. A typical case of a gout flare is presented. The role of the NLRP3 inflammasome in acute monosodium urate crystal‐induced inflammation is reviewed in detail.
Raewyn Poulsen, Nicola Dalbeth
wiley   +1 more source

Mitochondria and Endoplasmic Reticulum Contact Site as a Regulator of Proteostatic Stress Responses in Neurodegenerative Diseases

open access: yesBioEssays, EarlyView.
Recent findings indicate that mitochondria‐associated membranes (MAMs), where the endoplasmic reticulum directly contacts the mitochondria, are a novel microdomain essential for cellular homeostasis, including proteostasis. We summarize the disruption of protein homeostasis and MAM alteration in neurodegenerative diseases, then discuss challenges and ...
Seiji Watanabe, Koji Yamanaka
wiley   +1 more source

Aβ<sub>42</sub> induces stress granule formation via PACT/PKR pathway. [PDF]

open access: yesSci Rep
Ramasamy VS   +4 more
europepmc   +1 more source

Biomolecular phase separation in stress granule assembly and virus infection. [PDF]

open access: yesActa Biochim Biophys Sin (Shanghai), 2023
Liu Y, Yao Z, Lian G, Yang P.
europepmc   +1 more source

Hydrogen peroxide induces stress granule formation independent of eIF2α phosphorylation [PDF]

open access: green, 2012
Mohamed M. Emara   +5 more
openalex   +1 more source

Annexin, a Protein for All Seasons: From Calcium Dependent Membrane Metabolism to RNA Recognition

open access: yesBioEssays, EarlyView.
Annexins are an important protein family traditionally well known to bind to phospholipids and to interact with various proteins in a calcium dependent way. More recently, it has been established that a feature common to the family is also to bind to RNA having a role in translation. In bies70019 article, Vedeler et al.
Anni Vedeler   +2 more
wiley   +1 more source

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