Results 321 to 330 of about 129,858 (349)
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Yeast stress granules at a glance
Yeast, 2021AbstractThe formation of stress granules (SGs), membrane‐less organelles that are composed of mainly messenger ribonucleoprotein assemblies, is the result of a conserved evolutionary strategy to cellular stress. During their formation, which is triggered by robust environmental stress, SGs sequester translationally inactive mRNA molecules, which are ...
Tomas Grousl +3 more
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2022
Stress granules (SGs) are cytosolic ribonucleoprotein granules that form via a liquid-liquid phase separation in response to environmental stresses such as heat, oxidative, and osmotic changes. Due to the condensation of low complexity, hydrophobic regions in core SG components in these highly dynamic granules, defects in SG maintenance and formation ...
Elizabeth J, Alexander, Jiou, Wang
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Stress granules (SGs) are cytosolic ribonucleoprotein granules that form via a liquid-liquid phase separation in response to environmental stresses such as heat, oxidative, and osmotic changes. Due to the condensation of low complexity, hydrophobic regions in core SG components in these highly dynamic granules, defects in SG maintenance and formation ...
Elizabeth J, Alexander, Jiou, Wang
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mRNPs: From informosomes to stress granules
Molecular Biology, 2010Eucaryotic cytoplasmic mRNPs named when discovered "informosomes" are intensively investigated now as different mRNP granules. This review contains the data on structure and functioning of these mRNPs. The status of mRNA depends on spectrum of bound proteins and changes by signaling pathways.
A S, Voronina, E S, Pshennikova
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Mammalian Stress Granules and Processing Bodies
2007The packaging of cytoplasmic mRNA into discrete RNA granules regulates gene expression by delaying the translation of specific transcripts. Specialized RNA granules found in germ cells direct the timing of maternal mRNA translation to promote germ cell development in the early embryo and establish the germ line for the next generation.
Nancy, Kedersha, Paul, Anderson
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Molecular and Cellular Biochemistry, 2018
Stress granules are evolutionally conserved ribonucleoprotein structures that are formed in response to various stress stimuli. Recent studies have demonstrated that proteins with low complexity (LC) regions play a critical role for the formation of stress granules.
Kanako Ozeki +5 more
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Stress granules are evolutionally conserved ribonucleoprotein structures that are formed in response to various stress stimuli. Recent studies have demonstrated that proteins with low complexity (LC) regions play a critical role for the formation of stress granules.
Kanako Ozeki +5 more
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Chronic stress antagonizes formation of Stress Granules
AbstractChronic stress mediates cellular changes that can contribute to human disease. However, fluctuations in RNA metabolism caused by chronic stress have been largely neglected in the field. Stress granules (SGs) are cytoplasmic ribonucleoprotein condensates formed in response to stress-induced inhibition of mRNA translation and polysome disassembly.Yuichiro Adachi +5 more
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Ubiquitination of G3BP1 mediates stress granule disassembly in a context-specific manner
Science, 2021Youngdae Gwon +2 more
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The NK cell granule protein NKG7 regulates cytotoxic granule exocytosis and inflammation
Nature Immunology, 2020Susanna S Ng +2 more
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Enhanced synaptic plasticity in newly generated granule cells of the adult hippocampus
Nature, 2004Christoph Schmidt-Hieber +2 more
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