Results 171 to 180 of about 3,973,918 (385)

Sustainable Flame‐Retardant Poly Lactic Acid Biocomposites Reinforced with Polyphosphate‐Enriched Microalgae: Unlocking the Potential of Hyper‐Compensation

open access: yesAdvanced Sustainable Systems, EarlyView.
This study explores microalgae cultivation for wastewater treatment and enhancement of poly lactic acid (PLA)‐based biocomposites. It achieves up to 99.9% nutrient removal, increases biomass productivity by 322%, and demonstrates a triphasic luxury phosphorus uptake system. Incorporation into PLA improves fire‐retardant properties, suggesting potential
Rohit Dey   +9 more
wiley   +1 more source

A quantitative screen for metabolic enzyme structures reveals patterns of assembly across the yeast metabolic network. [PDF]

open access: yes, 2019
Despite the proliferation of proteins that can form filaments or phase-separated condensates, it remains unclear how this behavior is distributed over biological networks. We have found that 60 of the 440 yeast metabolic enzymes robustly form structures,
Begovich, Kyle   +5 more
core   +3 more sources

C9ORF72 Regulates Stress Granule Formation and Its Deficiency Impairs Stress Granule Assembly, Hypersensitizing Cells to Stress

open access: yesMolecular Neurobiology, 2016
Hexanucleotide repeat expansions in the C9ORF72 gene are causally associated with frontotemporal lobar dementia (FTLD) and/or amyotrophic lateral sclerosis (ALS). The physiological function of the normal C9ORF72 protein remains unclear. In this study, we characterized the subcellular localization of C9ORF72 to processing bodies (P-bodies) and its ...
Niran Maharjan   +3 more
openaire   +4 more sources

Stress Granules and Processing Bodies in Translational Control.

open access: yesCold Spring Harbor Perspectives in Biology, 2018
Stress granules (SGs) and processing bodies (PBs) are non-membrane-enclosed RNA granules that dynamically sequester translationally inactive messenger ribonucleoprotein particles (mRNPs) into compartments that are distinct from the surrounding cytoplasm.
P. Ivanov, N. Kedersha, P. Anderson
semanticscholar   +1 more source

FUS Selectively Facilitates circRNAs Packing into Small Extracellular Vesicles within Hypoxia Neuron

open access: yesAdvanced Science, EarlyView.
This study aimed to unravel the role of FUS in the loading of functional circRNAs into neuronal sEVs under hypoxic conditions, which involves their aggregations in SGs and specific interaction between the FUS Zf_RanBP domain to regulate circRNA sorting in sEVs.
Jiankun Zang   +14 more
wiley   +1 more source

Nonlocal Granular Rheology: Role of Pressure and Anisotropy [PDF]

open access: yes, 2013
We probe the secondary rheology of granular media, by imposing a main flow and immersing a vane-shaped probe into the slowly flowing granulate. The secondary rheology is then the relation between the exerted torque T and rotation rate \omega of our probe.
arxiv   +1 more source

The 5' → 3' exoribonuclease XRN1/Pacman and its functions in cellular processes and development [PDF]

open access: yes, 2012
XRN1 is a 5' → 3' processive exoribonuclease that degrades mRNAs after they have been decapped. It is highly conserved in all eukaryotes, including homologs in Drosophila melanogaster (Pacman), Caenorhabditis elegans (XRN1), and Saccharomyces cerevisiae (
Jones, Christopher Iain   +2 more
core   +1 more source

Keeping stress granules in check [PDF]

open access: yesScience, 2018
Neurodegeneration Stress granules are membraneless organelles composed of RNAs and proteins that can accumulate in the presence of potentially pathogenic proteins. These include proteins linked to neurodegenerative disorders such as C9-ALS/FTD (amyotrophic lateral sclerosis and frontotemporal dementia linked to C9ORF72).
openaire   +1 more source

PARP10 is Critical for Stress Granule Initiation

open access: yes, 2023
ABSTRACTStress granules (SGs) are cytoplasmic biomolecular condensates enriched with RNA, translation factors, and other proteins. They form in response to stress and are implicated in various diseased states including viral infection, tumorigenesis, and neurodegeneration.
Aravinth Kumar Jayabalan   +2 more
openaire   +2 more sources

Revisiting the Concept of Stress in the Prognosis of Solid Tumors: A Role for Stress Granules Proteins?

open access: yesCancers, 2020
Simple Summary Stress Granules (SGs) were discovered in 1999 and while the first decade of research has focused on some fundamental questions, the field is now investigating their role in human pathogenesis.
A. Aulas   +6 more
semanticscholar   +1 more source

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