Results 51 to 60 of about 1,437,001 (231)

ISOGEOMETRIC ANALYSIS OF STRESS INTENSITY FACTOR IN V-NOTCHED PLANE

open access: yesJixie qiangdu, 2022
In this paper, an isogeometric analysis method is proposed to obtain the notch tip stress intensity factor for the plane fracture problem with V-notch.
XU Wang, ZHONG DongWang, CAI LuJun
doaj  

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

open access: yesFEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang   +8 more
wiley   +1 more source

Stress Intensity Factors - T-Stresses - Weight Functions

open access: yes, 2008
Failure of cracked components is governed by the stresses in the vicinity of the crack tip. The singular stress contribution is characterised by the stress intensity factor K, the first regular stress term is represented by the so-called T-stress. Sufficient information about the stress state is available, if these two parameters are known Results for ...
openaire   +5 more sources

A new formulation for estimating maximum stress intensity factor at the mid plane of a SENB specimen: Study based on 3D FEA

open access: yesFracture and Structural Integrity, 2014
In this investigation, three-dimensional elastic finite element analyses have been conducted to compute the stress intensity factor (KI) in a SENB specimen with varied thickness (B) and crack-length to width ratio (a/W).
S. K. Kudari, K. G. Kodancha
doaj  

Stress and Displacement Intensity Factors of Cracks in Anisotropic Media

open access: yesInternational Journal of Applied Mechanics and Engineering, 2020
A relation connecting stress intensity factors (SIF) with displacement intensity factors (DIF) at the crack front is derived by solving a pseudodifferential equation connecting stress and displacement discontinuity fields for a plane crack in an elastic ...
S. Kuznetsov, A. Karakozova
doaj   +1 more source

Criticality of porosity defects on the fatigue performance of wire + arc additive manufactured titanium alloy [PDF]

open access: yes, 2019
This study was aimed at investigating the effect of internal porosity on the fatigue strength of wire + arc additive manufactured titanium alloy (WAAM Ti-6Al-4V).
Awd, Mustafa   +6 more
core   +2 more sources

Function‐driven design of a surrogate interleukin‐2 receptor ligand

open access: yesFEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang   +9 more
wiley   +1 more source

Measurement of the stress intensity factor and the effective stress intensity factor range of a mode I surface crack using the digital image correlation method

open access: yesNihon Kikai Gakkai ronbunshu, 2016
Crack opening displacement around a mode I surface crack tip was measured by digital image correlation method to determine the stress intensity factor and the effective stress intensity factor range.
Yuichi ONO   +2 more
doaj   +1 more source

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