Results 81 to 90 of about 3,042,639 (351)

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source

Anisotropic wave velocities of granular materials and microscopic fabric using X-ray computed tomography

Yantu gongcheng xuebao
The anisotropy of wave velocities of granular materials is investigated from both the macroscopic and microscopic scales. The effects of stress states on the P- and S-wave velocities propagating along multiple directions in granular samples of PVC ...
LIANG Xiaomin 1, GU Xiaoqiang 1, ZHAI Chongpu 2, WEI Deheng 3
doaj   +1 more source

Shear-stress intensity factors for elastic sheets with cover plates [PDF]

Shear stress intensity factors are calculated for three problems concerning inextensible cover plates either bonded to or embedded in an elastic sheet which is under uniaxial tension.
Fichter, W. B.
core   +1 more source

Scaling of the Strain Hardening Modulus of Glassy Polymers with the Flow Stress

, 2009
In a recent letter, Govaert et al. examined the relationship between strain hardening modulus $G_r$ and flow stress $\sigma_{flow}$ for five different glassy polymers.
Argon, Arruda, Auhl, Chen, Dupaix, Everaers, G'sell, Govaert, Hoy, Hoy, Hoy, Klompen, Kramer, Kremer, Li, Lyulin, Mulliken, Ree, Rottler, Rottler, Sarva, Sukumaran, Treloar, van Melick, Wendlandt, Yang   +25 more
core   +3 more sources

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

Molecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath, Irene A. George, Srikanth S. Manda, Prasanth Ariyannur, Ekta R. Dhawale, Raja Sekhar Kommu, Rajan Datar, Darshana Patil, Vinita Trivedi, Manisha Singh, Kumar Prabhash, Sewanti Limaye, Richa Chauhan, Prashant Kumar   +13 more
wiley   +1 more source

True triaxial test and failure criterion of coal gangue concrete

Meitan xuebao
In view of the pollution caused by the large storage of coal gangue and the shortage of natural aggregate in concrete, using coal gangue as coarse aggregate is a reasonable way to solve the above problems.
Weiping ZHAO, Yuxiang HE, Kongliang JIANG, Jiaqi YANG, Yang XU, Jialong CHEN   +5 more
doaj   +1 more source

Emerging role of ARHGAP29 in melanoma cell phenotype switching

Molecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster, Melanie Kappelmann‐Fenzl, Anja Katrin Bosserhoff, Nicole Rachinger   +3 more
wiley   +1 more source

Some Effects on Fatigue Strength

Acta Polytechnica, 2006
It has been widely known for some time that the mean stress affects the fatigue strength of steel. This is distinctly evident when working with non-welded or stress-relieved welded details. Some consequences of this influence are revealed when evaluating
P. Brož
doaj  

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source

The Effect of Multiple Factors on the Fatigue Crack Growth Behavior of DH36 Steel in Arctic Environment

Journal of Marine Science and Engineering
In Arctic regions, ship structures face low temperatures, overloads, thickness effects, and fluctuating stress ratios, which significantly influence the fatigue crack growth (FCG) behavior of marine steels.
Kaiqing Qiao, Zhijie Liu, Zhenyu Sun, Qiuyu Guo, Xiaobang Wang   +4 more
doaj   +1 more source