Results 81 to 90 of about 1,921,038 (288)
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
Measuring nonlinear stresses generated by defects in 3D colloidal crystals
, 2016 The mechanical, structural and functional properties of crystals are determined by their defects and the distribution of stresses surrounding these defects has broad implications for the understanding of transport phenomena. When the defect density rises
Bierbaum, Matthew +4 more
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Quasiharmonic elastic constants corrected for deviatoric thermal stresses [PDF]
, 2008 The quasiharmonic approximation (QHA), in its simplest form also called the statically constrained (SC) QHA, has been shown to be a straightforward method to compute thermoelastic properties of crystals.
D. C. Wallace +9 more
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FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
ALGORITHM FOR MODELING THE STRESS-DEFORMED STATE OF BENDED-RIGID THREADS
Модели, системы, сети в экономике, технике, природе и обществе, 2022 Background. An algorithm is proposed for modeling the distribution of stresses and strains, taking into account the bending stiffness in elements for which the design model is a thread. Materials and methods.
D.A. Tarasov +2 more
doaj +1 more source
Accurate computation of surface stresses and forces with immersed boundary methods [PDF]
, 2016 Many immersed boundary methods solve for surface stresses that impose the velocity boundary conditions on an immersed body. These surface stresses may contain spurious oscillations that make them ill-suited for representing the physical surface stresses ...
Colonius, Tim +3 more
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Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
AgronomyTIR1/AFB proteins are a class of auxin receptors with key roles in plant development and biotic and abiotic stress responses; several have been identified as targets of the auxin-mimicking herbicide picloram.
Wenchao Du +10 more
doaj +1 more source
Pavement stresses due to tire impact [PDF]
, 1995 Road surfaces wear continually under the effects of vehicular motions in an environment of changing temperature, humidity, etc. Regulatory agencies need to set limits on vehicular loads, tire pressures, etc., in order to mitigate the damage caused by the
Cumberbatch, E., Schichtel, M.
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