Results 161 to 170 of about 325,395 (379)

Ictal emotional features in pediatric and young adult patients with frontal lobe epilepsy

open access: yesEpilepsia Open, EarlyView.
Abstract Objective To assess the localization and lateralization values of ictal emotional features and ictal defensive behaviors in pediatric and young adult patients with frontal lobe epilepsy (FLE). Methods Children and young adults with FLE were identified from a single institution's epilepsy surgery database.
Ming‐Chen Tsai   +6 more
wiley   +1 more source

THE EFFECT OF SINGLE COMPLEX INTOXICATION WITH MORPHINE AND ALCOHOL ON THE CONTENT OF NEUROACTIVE AMINO ACIDS IN THE BRAIN OF RATS

open access: yesŽurnal Grodnenskogo Gosudarstvennogo Medicinskogo Universiteta, 2020
Background. Cases of combined consumption of surfactants (alcohol and opiates) in both the adult population and adolescents are quite common at present.
Velichko I. M.   +2 more
doaj   +1 more source

Exploring the Neuroprotective Role of Selenium: Implications and Perspectives for Central Nervous System Disorders

open access: yesExploration, EarlyView.
Selenium (Se) is a crucial element in selenoproteins, key biomolecules for physiological function in vivo. Central nervous system can express all 25 kinds of selenoproteins, which protect neurons by reducing oxidative stress and inflammatory response. Neuroprotection is being investigated through the biological study of Se.
Guanning Huang   +4 more
wiley   +1 more source

A Dopamine-Acetylcholine Cascade: Simulating Learned and Lesion-Induced Behavior of Striatal Cholinergic Interneurons [PDF]

open access: yes, 2007
The "teaching signal" that modulates reinforcement learning at cortico-striatal synapses may be a sequence composed of an adaptively scaled DA burst, a brief ACh burst, and a scaled ACh pause.
Bullock, Daniel, Tan, Can Ozan
core   +1 more source

Oligodendrogenesis in Evolution, Development and Adulthood

open access: yesGlia, EarlyView.
Oligodendrocytes and myelin took shape in jawed vertebrates. During development, OPCs are originated from NSCs and then undergo differentiation into mature oligodendrocytes that supply myelin. OPCs persist in the adult CNS and continue to produce oligodendrocytes and myelin. Adaptive myelination, which fine‐tunes neural circuits in response to neuronal
Hao Hu   +3 more
wiley   +1 more source

Spatial Transcriptomic Analysis Reveals HDAC Inhibition Modulates Microglial Dynamics to Protect Against Ischemic Stroke in Mice

open access: yesGlia, EarlyView.
Spatial transcriptomic analysis unravels the mechanisms by which HDACi ameliorates neuroinflammation and enhances neuroprotection by modulating the expression of microglial transcriptomes in the ischemic mouse brain. ABSTRACT Ischemic stroke significantly contributes to global morbidity and disability through a cascade of neurological responses ...
Kevin Jayaraj   +5 more
wiley   +1 more source

Microglial Activation and Inflammatory Responses in Parkinson's Disease Models Are Attenuated by TRPM2 Depletion

open access: yesGlia, EarlyView.
Trpm2 partial and complete knockout reduce neuroinflammation in male and female mice. Microglial morphological changes are not found in Trpm2 knockout 6‐OHDA‐induced mice. TRPM2 is involved in microglial phagocytosis and IL1β, IL6, and iNOS expression. ABSTRACT Inflammation, and particularly microglial cells, has become a central feature in Parkinson's
Ana Flávia F. Ferreira   +3 more
wiley   +1 more source

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