Results 181 to 190 of about 325,395 (379)

MR‐Guidance of Gene Therapy for Brain Diseases: Moving From Palliative Treatment to Cures

open access: yesJournal of Magnetic Resonance Imaging, EarlyView.
ABSTRACT Regulatory bodies in the U.S. and Europe recently approved a gene therapy for aromatic L‐amino acid decarboxylase (AADC) deficiency, a rare neurologic disorder where a genetic mutation prevents dopamine production in the brain. Affected children fail to develop normal motor and cognitive functions.
Dalton H. Bermudez   +2 more
wiley   +1 more source

“MR Fingerprinting for Imaging Brain Hemodynamics and Oxygenation”

open access: yesJournal of Magnetic Resonance Imaging, EarlyView.
ABSTRACT Over the past decade, several studies have explored the potential of magnetic resonance fingerprinting (MRF) for the quantification of brain hemodynamics, oxygenation, and perfusion. Recent advances in simulation models and reconstruction frameworks have also significantly enhanced the accuracy of vascular parameter estimation.
T. Coudert   +6 more
wiley   +1 more source

Mass spectrometry imaging of N‐linked glycans: Fundamentals and recent advances

open access: yesMass Spectrometry Reviews, EarlyView.
Abstract With implications in several medical conditions, N‐linked glycosylation is one of the most important posttranslation modifications present in all living organisms. Due to their nontemplate synthesis, glycan structures are extraordinarily complex and require multiple analytical techniques for complete structural elucidation.
Tana V. Palomino, David C. Muddiman
wiley   +1 more source

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