Results 81 to 90 of about 325,395 (379)

Logarithmic distributions prove that intrinsic learning is Hebbian

open access: yes, 2017
In this paper, we present data for the lognormal distributions of spike rates, synaptic weights and intrinsic excitability (gain) for neurons in various brain areas, such as auditory or visual cortex, hippocampus, cerebellum, striatum, midbrain nuclei ...
Scheler, Gabriele
core   +2 more sources

Machine‐Learning‐Aided Advanced Electrochemical Biosensors

open access: yesAdvanced Materials, EarlyView.
Electrochemical biosensors are highly sensitive, portable, and versatile. Advanced nanomaterials enhance their performance, while machine learning (ML) improves data analysis, minimizes interference, and optimizes sensor design. Despite progress in both fields, their combined potential in diagnostics remains underexplored.
Andrei Bocan   +9 more
wiley   +1 more source

Striatal fast-spiking interneurons selectively modulate circuit output and are required for habitual behavior

open access: yeseLife, 2017
Habit formation is a behavioral adaptation that automates routine actions. Habitual behavior correlates with broad reconfigurations of dorsolateral striatal (DLS) circuit properties that increase gain and shift pathway timing.
Justin K O'Hare   +7 more
doaj   +1 more source

Disruption of Nrxn1α within excitatory forebrain circuits drives value-based dysfunction

open access: yeseLife, 2020
Goal-directed behaviors are essential for normal function and significantly impaired in neuropsychiatric disorders. Despite extensive associations between genetic mutations and these disorders, the molecular contributions to goal-directed dysfunction ...
Opeyemi O Alabi   +6 more
doaj   +1 more source

17β-estradiol does not have a direct effect on the function of striatal cholinergic interneurons in adult mice in vitro

open access: yesFrontiers in Endocrinology, 2023
The striatum is an essential component of the basal ganglia that is involved in motor control, action selection and motor learning. The pathophysiological changes of the striatum are present in several neurological and psychiatric disorder including ...
Erzsébet Kövesdi   +17 more
doaj   +1 more source

Dopamine neurons projecting to the posterior striatum form an anatomically distinct subclass

open access: yeseLife, 2015
Combining rabies-virus tracing, optical clearing (CLARITY), and whole-brain light-sheet imaging, we mapped the monosynaptic inputs to midbrain dopamine neurons projecting to different targets (different parts of the striatum, cortex, amygdala, etc) in ...
William Menegas   +7 more
semanticscholar   +1 more source

Dorsomedial striatum, but not dorsolateral striatum, is necessary for rat category learning

open access: yesNeurobiology of Learning and Memory, 2023
Categorization is an adaptive cognitive function that allows us to generalize knowledge to novel situations. Converging evidence from neuropsychological, neuroimaging, and neurophysiological studies suggest that categorization is mediated by the basal ganglia; however, there is debate regarding the necessity of each subregion of the basal ganglia and ...
Matthew B. Broschard   +3 more
openaire   +3 more sources

Harnessing Photo‐Energy Conversion in Nanomaterials for Precision Theranostics

open access: yesAdvanced Materials, EarlyView.
Harnessing photo‐energy conversion in nanomaterials enables precision theranostics through light‐driven mechanisms such as photoluminescence, photothermal, photoelectric, photoacoustic, photo‐triggered surface‐enhanced Raman scattering (SERS), and photodynamic processes. This review explores six fundamental principles of photo‐energy conversion, recent
Jingyu Shi   +4 more
wiley   +1 more source

Secretagogin expression delineates functionally-specialized populations of striatal parvalbumin-containing interneurons

open access: yeseLife, 2016
Corticostriatal afferents can engage parvalbumin-expressing (PV+) interneurons to rapidly curtail the activity of striatal projection neurons (SPNs), thus shaping striatal output.
Farid N Garas   +9 more
doaj   +1 more source

Trusting outgroup, but not ingroup members, requires control: neural and behavioral evidence. [PDF]

open access: yes, 2016
Trust and cooperation often break down across group boundaries, contributing to pernicious consequences, from polarized political structures to intractable conflict.
Ambady, Nalini   +2 more
core   +2 more sources

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