Results 51 to 60 of about 388,862 (296)
Finding novel vulnerabilities of hypomorphic BRCA1 alleles
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder +10 more
wiley +1 more source
Influence of local displacements and stresses on combined string structure
The article discusses the combined string construction of a single span. 2 load methods are analyzed when the structure is loaded with a distributed load and when the structure is loaded with concentrated loads on the struts.
Edmundas Beivydas
doaj +1 more source
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi +6 more
wiley +1 more source
Wave propagation in a non-uniform string
In this article I present the behavior of the reflection and transmission coefficients of a pulse at a joint between two strings with mass densities μ1and μ2. The joint is made of a string segment with mass density varying linearly from μ1 to μ2. It will
Fernando Fuzinatto Dall'Agnol
doaj +1 more source
When an elevator rope for a high-rise building is forcibly excited by the displacements of the building induced by wind forces and/or by long-period ground motion, rope displacement becomes large even if the ground acceleration and the buildings ...
Hiroyuki KIMURA
doaj +1 more source
String field theory of noncritical strings [PDF]
13 pages ( LaTex file ), KEK-TH-364, UT ...
Ishibashi, Nobuyuki, Kawai, Hikaru
openaire +2 more sources
Models of Macroeconomic Systems using Genetic Algorithms [PDF]
AG represents only one, it’s true that it is very fashionable today, of the new instruments which began to be used lately in the macroeconomic modelling. Here, it may also be mentioned the classification systems, the genetic programming, the models based
Nora Mihail
doaj +1 more source
Free vibration analysis of string with vibration suppressors located in center part of string
Vibration suppressors are used to change the natural frequency of an elevator rope and prevent resonance. The displacement of the parts of the elevator rope at both the ends is small compared to that of the center part of the rope; therefore, it is not ...
Hiroyuki KIMURA, Takahiro FUJITANI
doaj +1 more source
Jean Cleymans, Stringy Thermal Model, Tsallis Quantum Statistics
My memories on Jean Cleymans and a brief advocation of the stringy thermal model, describing massless constituents with the energy-per-particle and temperature relation, E/N=6T=1 GeV, are presented. Another topic, the Kubo–Martin–Schwinger (KMS) relation
Tamás S. Biró
doaj +1 more source
This article, written for Scolarpedia, provides a brief introduction into the subject of cosmic strings, together with a review of their main properties, cosmological evolution and observational signatures.
Tanmay Vachaspati +2 more
openaire +3 more sources

