Results 21 to 30 of about 5,180,263 (277)

Stroke-Like episodes and epilepsy in a patient with COQ8A-Related coenzyme Q10 deficiency

Annals of Indian Academy of Neurology, 2023
Coenzyme q10 (CoQ10) deficiency is an extremely uncommon disease that has very rarely been reported in adulthood. This case describes an elderly male with ataxia since adolescence, and visual disturbance since 40, presenting with recurrent episodes of ...
Rithvik Ramesh, Sundar Hariharan, Latha Sundar   +2 more
doaj   +1 more source

Mitochondrial stroke-like episodes: The search for new therapies

Pharmacological Research, 2022
A mitochondrial stroke-like event is an evolving subacute neurological syndrome linked to seizure activity and focal metabolic brain derangement in a genetically determined mitochondrial disorder. The acronym "MELAS" (mitochondrial encephalopathy associated with lactic acidosis and stroke-like lesions) identifies subjects with molecular, biochemical ...
Orsucci, Daniele, Ienco, Elena Caldarazzo, Montano, Vincenzo, Siciliano, Gabriele, Mancuso, Michelangelo   +4 more
openaire   +4 more sources

Statistical analysis of the primary outcome in acute stroke trials [PDF]

, 2012
Common outcome scales in acute stroke trials are ordered categorical or pseudocontinuous in structure but most have been analyzed as binary measures. The use of fixed dichotomous analysis of ordered categorical outcomes after stroke (such as the modified
Lees, K.R., Saver, J.L., Howard, G., TONI, Danilo, Altman, H., Schellinger, P.D., Bland, M., Hogg, C., Bath, P.M.W., European Stroke Organisation Outcomes Working Group   +9 more
core   +1 more source

Rheumatoid meningitis presenting with stroke-like episodes [PDF]

Neurology, 2014
Neurologic symptoms in patients with rheumatoid arthritis (RA) are most often caused by osseous compression, affecting the cervical spine or peripheral neurologic structures. CNS involvement in RA is infrequent, consisting of CNS vasculitis or meningitis with or without meningeal nodules.(1) When meningeal infiltration is seen, symptoms of presentation
Pascale, Bourgeois, Jean, Rivest, Christian, Bocti   +2 more
openaire   +2 more sources

Forecasting stroke-like episodes and outcomes in mitochondrial disease [PDF]

Brain, 2021
AbstractIn this retrospective, multicentre, observational cohort study, we sought to determine the clinical, radiological, EEG, genetics and neuropathological characteristics of mitochondrial stroke-like episodes and to identify associated risk predictors.Between January 1998 and June 2018, we identified 111 patients with genetically determined ...
Yi Shiau Ng, Nichola Z Lax, Alasdair P Blain, Daniel Erskine, Mark R Baker, Tuomo Polvikoski, Rhys H Thomas, Christopher M Morris, Ming Lai, Roger G Whittaker, Alasdair Gebbels, Amy Winder, Julie Hall, Catherine Feeney, Maria Elena Farrugia, Claire Hirst, Mark Roberts, Charlotte Lawthom, Alexia Chrysostomou, Kevin Murphy, Tracey Baird, Paul Maddison, Callum Duncan, Joanna Poulton, Victoria Nesbitt, Michael G Hanna, Robert D S Pitceathly, Robert W Taylor, Emma L Blakely, Andrew M Schaefer, Doug M Turnbull, Robert McFarland, Gráinne S Gorman   +32 more
openaire   +4 more sources

MELAS with multiple stroke‐like episodes due to the variant m.13513G>A in MT‐ND5

Clinical Case Reports, 2022
Mitochondrial encephalopathy, lactic acidosis, and stroke‐like episodes (MELAS) is characterized by metabolic stroke, seizures, cognitive decline, lactic acidosis, ragged‐red fibers, headache, and vomiting, and in 80% of cases due to the mtDNA variant m ...
Ritwik Ghosh, Souvik Dubey, Subhas Bhuin, Durjoy Lahiri, Biman Kanti Ray, Josef Finsterer   +5 more
doaj   +1 more source

Contemporary outcome measures in acute stroke research: choice of primary outcome measure [PDF]

, 2012
BACKGROUND AND PURPOSE: The diversity of available outcome measures for acute stroke trials is challenging and implies that the scales may be imperfect.
D. m. Kerr, R. Fulton, Matchar, D., D. Matchar, K. r. Lees, Schellinger, P., Bath, P.M.W., P. m. w. Bath, Lees, K.R., Kerr, D.M., Toni, D., TONI, Danilo, Sehra, R., R. Sehra, Hacke, W., P. d. Schellinger, Fulton, R., W. Hacke, Hacke, Werner, European Stroke Organization Outcomes Working Group, Kerr, Daniel M, Fulton, Rachael, Matchar, David, Schellinger, Peter D, Sehra, Ruchir, Bath, Philip MW, Lees, Kennedy R   +26 more
core   +1 more source

Nonbiomedical stroke practitioners in Aceh [PDF]

, 2011
This is the accepted version of the following article: Norris, M., Allotey, P. and Barrett, G. (2011), Nonbiomedical stroke practitioners in Aceh. International Journal of Stroke, 6: 152–154.
Allotey, P, Barrett, G
core   +1 more source

Systemic Sarcoidosis Presenting with Headache and Stroke-Like Episodes [PDF]

Case Reports in Immunology, 2015
Sarcoidosis is a multisystem granulomatous disorder. Neurological manifestations as a presenting symptom are relatively rare. A 26-year-old male presented with a five-week history of headache suggestive of raised intracranial pressure. He subsequently developed transient episodes of mild right-sided hemiparesis and numbness. Magnetic resonance imaging (
Campbell, J., Kee, R., Bhattacharya, D., Flynn, P., McCarron, M., Fulton, A.   +5 more
openaire   +5 more sources

Commentary: Profiles of paediatric patients experiencing stroke-like episodes associated with mitochondrial disease [PDF]

Frontiers in Neurology
Josef Finsterer
doaj   +2 more sources