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The Effect of Stromal Cell-Derived Factor 1 in the Migration of Neural Stem Cells
Cell Biochemistry and Biophysics, 2014Neural stem cells (NSCs) have widely been used in the treatment of human neurological disorders as cell therapy via intracerebral or intraventricular infusion. However, the migration mechanism required for NSCs homing and recruitment remains to be elucidated.
Liping, Xue +6 more
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Stromal Cell‐Derived Factor‐1 Alpha Is Decreased in Women With Migraine With Aura
Headache: The Journal of Head and Face Pain, 2016Background Endothelial dysfunction may contribute to the pathophysiology of migraine with aura. Stromal cell‐derived factor‐1 alpha (SDF‐1α) is involved in the maintenance of endothelial integrity via mobilization of vascular stem cells. Objectives
Liman, Thomas G +4 more
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Neutrophil Homeostasis: A New Role for Stromal Cell–Derived Factor-1
Immunologic Research, 2005Neutrophils are a key component of the innate immune response and a major contributor to inflammation. Accordingly, their number in the blood is tightly controlled. Neutrophils are normally produced exclusively in the bone marrow, and their release into the blood is tightly regulated to maintain homeostatic levels in the blood.
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Increase of circulating stromal cell-derived factor-1 in heart failure patients
Herz, 2014The role of circulating stromal cell-derived factor-1 (SDF-1) in heart failure (HF) has not been defined. The aim of this study was to examine the circulating SDF-1 levels in hospitalized heart failure (HHF) patients.Circulating SDF-1 and other clinical variables, including N-terminal pro-brain natriuretic peptide (NT-proBNP), C-reactive protein (CRP),
K, Liu +5 more
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Identification of a potential modification site in human stromal cell‐derived factor‐1
Peptide Science, 2010AbstractSelective modification of proteins is an important tool to study their function. However, it is still challenging to identify the best position to avoid a loss of activity. By using a 6‐nitroveratryl (Nvoc)‐modification approach, we facilitate the identification of a potential modification site as Nvoc can be removed in situ by UV irradiation ...
Lars, Baumann, Annette G, Beck-Sickinger
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Identification and expression of novel isoforms of human stromal cell-derived factor 1
Gene, 2006Stromal Cell-derived factor 1 (SDF-1) is a CXC chemokine that binds to the CXCR4 receptor. Recent publication indicates that the SDF-1/CXCR4 signaling pathway plays a pivotal role during development and in many patho-physiological conditions including hematopoiesis, blood vessel formation, cancer metastasis, angiogenesis and HIV infection.
Lan, Yu +7 more
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Stromal Cell Derived Factor-1 and Long-Term Prognosis in Acute Coronary Syndrome
Biomarkers in Medicine, 2019Aim: To explore long-term prognostic value of SDF-1 in acute coronary syndrome (ACS). Materials & methods: We included 254 patients with ACS. Plasma SDF-1 was measured and patients were classified into tertiles of SDF-1. Results: Multivariate analysis showed third tertile of SDF-1 as an independent predictor of all-cause death (HR: 2.5; 95% CI: 1.2-5.2;
Óscar M Peiró +6 more
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Therapeutic Delivery of Stromal Cell-Derived Factor-1 for Injury Repair
Nano LIFE, 2016Stromal cell-derived growth factor-1 (SDF1) is a chemokine that is over-expressed at sites of injury and is believed to play an important role in wound repair. At the cellular level, SDF1 regulates the mobilization and trafficking of endothelial progenitors that originate in the bone marrow and functionally contribute to neovascularization and ...
Agnes Yeboah +2 more
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CXCL12/Stromal Cell-Derived Factor-1 and Hematopoiesis
2023Maegan L. Capitano +2 more
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