Results 251 to 260 of about 313,405 (294)

Biphasic expression of stromal cell-derived factor-1 during human wound healing

British Journal of Dermatology, 2007
Chemokines tightly regulate the spatial and temporal infiltration of invading leucocyte subsets during wound healing. Stromal cell-derived factor-1 (SDF-1/CXCL12) is a homeostatic chemokine with multiple functions; its role during cutaneous wound healing, however, needs to be explored.To elucidate expression of the multifunctional CXC chemokine SDF-1 ...
A, Toksoy, V, Müller, R, Gillitzer, M, Goebeler   +3 more
openaire   +2 more sources

Neutrophil Homeostasis: A New Role for Stromal Cell–Derived Factor-1

Immunologic Research, 2005
Neutrophils are a key component of the innate immune response and a major contributor to inflammation. Accordingly, their number in the blood is tightly controlled. Neutrophils are normally produced exclusively in the bone marrow, and their release into the blood is tightly regulated to maintain homeostatic levels in the blood.
openaire   +2 more sources

Increase of circulating stromal cell-derived factor-1 in heart failure patients

Herz, 2014
The role of circulating stromal cell-derived factor-1 (SDF-1) in heart failure (HF) has not been defined. The aim of this study was to examine the circulating SDF-1 levels in hospitalized heart failure (HHF) patients.Circulating SDF-1 and other clinical variables, including N-terminal pro-brain natriuretic peptide (NT-proBNP), C-reactive protein (CRP),
K, Liu, S, Yang, M, Hou, T, Chen, J, Liu, B, Yu   +5 more
openaire   +2 more sources

Epiphysiodesis with Infusion of Stromal Cell-Derived Factor-1 in Rabbit Growth Plates

The Journal of Bone & Joint Surgery, 2007
The mechanism of physeal closure is poorly understood, although both mechanical and biological factors may play a role in the process. In this study, we evaluated the effect of the application of a chemokine stromal cell-derived factor-1 (SDF-1) to rabbit physes in vivo with regard to growth inhibition.A continuous infusion system consisting of a ...
Mark C, Lee, Adam D, Bier, Florian, Nickisch, Craig P, Eberson, Michael G, Ehrlich, Qian, Chen   +5 more
openaire   +2 more sources

Therapeutic Delivery of Stromal Cell-Derived Factor-1 for Injury Repair

Nano LIFE, 2016
Stromal cell-derived growth factor-1 (SDF1) is a chemokine that is over-expressed at sites of injury and is believed to play an important role in wound repair. At the cellular level, SDF1 regulates the mobilization and trafficking of endothelial progenitors that originate in the bone marrow and functionally contribute to neovascularization and ...
Agnes Yeboah, Martin L. Yarmush, Francois Berthiaume   +2 more
openaire   +1 more source

Abstract 315: Stromal Cell-derived Factor 1 Protects From Diabetic Cardiomyopathy

Circulation Research, 2015
We have demonstrated that stromal cell-derived factor 1(SDF-1) protects against palmitate-induced cardiac apoptosis, which is mediated by NOX-activated nitrosative damage and endoplasmic reticulum stress, via CXCR7, to activate AMPK/p38 MAPK-mediated IL-6 generation (Diabetes 62:2545-2558, 2013).
Xiaoqing Yan, Shudong Wang, Jing Chen, Jun Chen, Jun Zeng, Yi Tan   +5 more
openaire   +1 more source

Stromal cell-derived factor-1 alpha alleviates hypoxic-ischemic brain damage in mice

Biochemical and Biophysical Research Communications, 2015
Hypoxic-ischemic brain damage (HIBD) is a major cause of acute deaths and chronic nervous system damage. There is good evidence that stromal cell-derived factor-1 alpha (SDF-1α) has been receiving much interest in its role in the treatment of ischemic diseases.
Qin, Yu, Liping, Zhou, Lizhen, Liu, Li, Cong, Yan, Wang, Tingting, Ge, Deju, Lin   +6 more
openaire   +2 more sources

Stromal Cell-Derived Factor 1 (SDF-1) Signaling and Tissue Homeostasis

2019
Stromal cell-derived factor 1 (SDF-1) or C-X-C motif chemokine 12 (CXCL12) is a highly potent chemoattractant and paracrine protein with critical roles in embryogenesis and hematopoiesis, as well as postnatal tissue repair and regeneration. It acts through the chemokine receptor 4 (CXCR4) and CXCR7 receptors to mediate chemotactic processes including ...
Zeshaan N. Maan, Mimi R. Borrelli, Khosrow Siamak Houschyar, Geoffrey C. Gurtner   +3 more
openaire   +1 more source

CXCL12/Stromal Cell-Derived Factor-1 and Hematopoiesis

2023
Maegan L. Capitano, James P. Ropa, Hal E. Broxmeyer   +2 more
openaire   +1 more source

Stromal cell-derived factor 1 expression in various skin tumours

British Journal of Dermatology, 2009
S-J, Chen, T, Nakahara, M, Kido, M, Takahara, H, Uchi, S, Takeuchi, L, Dugu, Y-T, Tu, Y, Moroi, M, Furue   +9 more
openaire   +2 more sources