Results 41 to 50 of about 313,405 (295)

Multi-Parameter Analysis of Biobanked Human Bone Marrow Stromal Cells Shows Little Influence for Donor Age and Mild Comorbidities on Phenotypic and Functional Properties [PDF]

, 2019
Heterogeneous populations of human bone marrow-derived stromal cells (BMSC) are among the most frequently tested cellular therapeutics for treating degenerative and immune disorders, which occur predominantly in the aging population.
Andrzejewska, Anastazja, Beez, Christien, Blankenstein, Antje, Catar, Rusan, Duda, Georg, Geissler, Sven, Jacobi, Dorit, Jürchott, Karsten, Kamhieh-Milz, Julian, Krüger, David, Krüger, Ulrike, Moll, Guido, Qazi, Taimoor Hasan, Reinke, Petra, Reinke, Simon, Richter, Sarina, Sass, Frauke Andrea, Schlickeiser, Stephan, Schoon, Janosch, Souidi, Naima, Streitz, Mathias, Strunk, Dirk, Zemojtel, Tomasz   +22 more
core   +1 more source

Therapeutic Potential of Mesenchymal Stem Cells for Cancer Therapy [PDF]

, 2020
Mesenchymal stem cells (MSCs) are among the most frequently used cell type for regenerative medicine. A large number of studies have shown the beneficial effects of MSC-based therapies to treat different pathologies, including neurological disorders ...
Capilla González, Vivian, Gauthier, Benoit R., Hmadcha, Abdelkrim, Martín Montalvo, Alejandro, Soria Escoms, Bernat   +4 more
core   +1 more source

Platelet-derived stromal cell-derived factor-1 is required for the transformation of circulating monocytes into multipotential cells. [PDF]

PLoS ONE, 2013
BACKGROUND: We previously described a primitive cell population derived from human circulating CD14(+) monocytes, named monocyte-derived multipotential cells (MOMCs), which are capable of differentiating into mesenchymal and endothelial lineages.
Noriyuki Seta, Yuka Okazaki, Hiroshi Miyazaki, Takashi Kato, Masataka Kuwana   +4 more
doaj   +1 more source

Role of SDF-1/CXCR4 in cancer-associated fibroblasts [PDF]

Jichu yixue yu linchuang, 2020
Cancer-associated fibroblasts (CAFs), important component of tumor microenvironment, secrete a variety of factors that play an important role in the occurrence and development of malignant tumors. Stromal cell derived factor-1(SDF-1) secreted by CAFs and
YU Biao, LIU Qing, WU Xiao-ming
doaj  

Axonal growth arrests after an increased accumulation of Schwann cells expressing senescence markers and stromal cells in acellular nerve allografts [PDF]

, 2016
Acellular nerve allografts (ANAs) and other nerve constructs do not reliably facilitate axonal regeneration across long defects (>3 cm). Causes for this deficiency are poorly understood.
Ee, Xueping, Hoben, Gwendolyn M, Hunter, Daniel A, Mackinnon, Susan E, Moore, Amy M, Pan, Deng, Poppler, Louis H, Schellhardt, Lauren, Snyder-Warwick, Alison K, Stewart, Sheila A, Wood, Matthew D, Yan, Ying   +11 more
core   +2 more sources

Matrix Metalloproteinase Activity Inactivates the CXC Chemokine Stromal Cell-derived Factor-1 [PDF]

Journal of Biological Chemistry, 2001
Chemokines provide directional cues for leukocyte migration and activation that are essential for normal leukocytic trafficking and for host responses during processes such as inflammation, infection, and cancer. Recently we reported that matrix metalloproteinases (MMPs) modulate the activity of the CC chemokine monocyte chemoattractant protein-3 by ...
G A, McQuibban, G S, Butler, J H, Gong, L, Bendall, C, Power, I, Clark-Lewis, C M, Overall   +6 more
openaire   +2 more sources

Stromal cell-derived factor: pathological and clinical potentialities [PDF]

РМЖ. Мать и дитя, 2020
O.V. Prokhorova1, A.A. Olina2, G.Kh. Tolibova2, T.G. Tral’2 1Ural State Medical University, Yekaterinburg, Russian Federation 2D.O. Ott Research Institute of Obstetrics, Gynecology & Reproduction, St.
O.V. Prokhorova, A.A. Olina, G.Kh. Tolibova, T.G. Tral   +3 more
doaj  

Characterization and profiling of immunomodulatory genes of equine mesenchymal stromal cells from non-invasive sources [PDF]

, 2014
Introduction: Mesenchymal stromal cells (MSCs) have been extensively studied for their promising capabilities in regenerative medicine. Although bone marrow is the best-known source for isolating equine MSCs, non-invasive alternative sources such as ...
De Schauwer, Catharina, Goossens, Karen, Govaere, Jan, Hoogewijs, Maarten, Meyer, Evelyne, Piepers, Sofie, Smits, Katrien, Van de Walle, Gerlinde, Van Soom, Ann   +8 more
core   +2 more sources

Increased immunoreactivity of stromal cell-derived factor‐1 and angiogenesis in asthma [PDF]

European Respiratory Journal, 2003
Stromal cell-derived factor‐1 (SDF‐1) acts as a chemoattractant for leukocytes and can induce neovascularisation. To examine the role of SDF‐1 in the development of angiogenesis, immunohistochemical studies were performed on bronchial biopsy specimens from asthmatic and control subjects.Bronchial biopsy specimens were obtained from 13 asthmatic and ...
M, Hoshino, N, Aoike, M, Takahashi, Y, Nakamura, T, Nakagawa   +4 more
openaire   +2 more sources

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source