Results 11 to 20 of about 333,204 (219)

Isolation of human bone marrow stromal cells from bone marrow biopsies for single-cell RNA sequencing

open access: yesSTAR Protocols, 2021
Summary: Bone marrow (BM) mesenchymal stromal cells play an important role in regulating stem cell quiescence and homeostasis; they are also key contributors to various hematological malignancies. However, human bone marrow stromal cells are difficult to
Hélène F.E. Gleitz   +4 more
doaj   +1 more source

CD271 antigen defines a subset of multipotent stromal cells with immunosuppressive and lymphohematopoietic engraftment-promoting properties

open access: yesHaematologica, 2010
Background In vitro proliferative and differentiation potential of mesenchymal stromal cells generated from CD271+ bone marrow mononuclear cells (CD271-mesenchymal stromal cells) has been demonstrated in several earlier and recent reports. In the present
Selim Kuçi   +16 more
doaj   +1 more source

Failure of intravenous or intracardiac delivery of mesenchymal stromal cells to improve outcomes after focal traumatic brain injury in the female rat. [PDF]

open access: yesPLoS ONE, 2015
Mesenchymal stromal cells secrete a variety of anti-inflammatory factors and may provide a regenerative medicine option for the treatment of traumatic brain injury.
L Christine Turtzo   +10 more
doaj   +1 more source

Bovine endometrial stromal cells display osteogenic properties

open access: yesReproductive Biology and Endocrinology, 2008
The endometrium is central to mammalian fertility. The endometrial stromal cells are very dynamic, growing and differentiating throughout the estrous cycle and pregnancy.
Cavirani Sandro   +4 more
doaj   +1 more source

Multipotent mesenchymal stromal cells from amniotic fluid: solid perspectives for clinical application

open access: yesHaematologica, 2008
Background Mesenchymal stromal cells are multipotent cells considered to be of great promise for use in regenerative medicine. However, the cell dose may be a critical factor in many clinical conditions and the yield resulting from the ex vivo expansion ...
Nadia Sessarego   +11 more
doaj   +1 more source

Mesenchymal Stromal Cells Support Endometriotic Stromal Cells In Vitro

open access: yesStem Cells International, 2018
Endometriosis is an inflammatory disease marked by ectopic growth of endometrial cells. Mesenchymal stromal cells (MSC) have immunosuppressive properties that have been suggested as a treatment for inflammatory diseases.
Fawaz Abomaray   +4 more
doaj   +1 more source

Expression of the melanoma cell adhesion molecule in human mesenchymal stromal cells regulates proliferation, differentiation, and maintenance of hematopoietic stem and progenitor cells

open access: yesHaematologica, 2013
The melanoma cell adhesion molecule defines mesenchymal stromal cells in the human bone marrow that regenerate bone and establish a hematopoietic microenvironment in vivo.
Sabine Stopp   +6 more
doaj   +1 more source

Multipotent stromal cells skew monocytes towards an anti-inflammatory interleukin-10-producing phenotype by production of interleukin-6

open access: yesHaematologica, 2013
Multipotent stromal cells have immunomodulatory capacities and have been used in transplantation and autoimmune diseases. One of the effects of multipotent stromal cells involves the inhibition of dendritic cell differentiation.
Sara M. Melief   +3 more
doaj   +1 more source

Emerging data supporting stromal cell therapeutic potential in cancer: reprogramming stromal cells of the tumor microenvironment for anti-cancer effects

open access: yesCancer Biology & Medicine, 2020
After more than a decade of controversy on the role of stromal cells in the tumor microenvironment, the emerging data shed light on pro-tumorigenic and potential anti-cancer factors, as well as on the roots of the discrepancies.
Armel H. Nwabo Kamdje   +5 more
doaj   +1 more source

Infection Programs Sustained Lymphoid Stromal Cell Responses and Shapes Lymph Node Remodeling upon Secondary Challenge

open access: yesCell Reports, 2017
Summary: Lymph nodes (LNs) are constructed of intricate networks of endothelial and mesenchymal stromal cells. How these lymphoid stromal cells (LSCs) regulate lymphoid tissue remodeling and contribute to immune responses remains poorly understood.
Julia L. Gregory   +12 more
doaj   +1 more source

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