Results 211 to 220 of about 4,473,212 (256)

Reinventing mesenchymal stromal cells

Cytotherapy, 2012
The life-saving impact of chemotherapy and radiation has been as remarkable and momentous as any advance in the history of medicine. This becomes even more signifi cant when we remind ourselves that 50 years ago nearly all leukemias, lymphomas and aggressive solid tumors were fatal, and that nearly everything in oncology before the 20th century was a ...
Jakub, Tolar, Miroslav, Tolar
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Mesenchymal stromal cells: an update

Current Opinion in Hematology
Purpose of review Mesenchymal stromal cells (MSCs) are widely utilized in preclinical and clinical studies, with over 1500 clinical trials, including applications in Covid-19 treatment. This review consolidates recent advances in understanding MSC biology, mechanisms of action, and clinical utility.
Olivia J, Lee, Armand, Keating
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Stromal Cells in the Tumor Microenvironment

2018
The tumor microenvironment comprises a mass of heterogeneous cell types, including immune cells, endothelial cells, and fibroblasts, alongside cancer cells. It is increasingly becoming clear that the development of this support niche is critical to the continued uncontrolled growth of the cancer.
Denton, A. E., Roberts, E. W., Fearon, D. T.   +2 more
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Decidualisation of cervical stromal cells

European Journal of Obstetrics & Gynecology and Reproductive Biology, 2004
Control of cervical function is poorly understood. The major structural component of the cervix is collagen and peri-partum cervical changes are largely due to the action of collagenase, either released by resident cells or derived from an influx of neutrophils.
Shona, Cowan, Andrew A, Calder, Rodney W, Kelly   +2 more
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The CD9 Molecule on Stromal Cells

Leukemia & Lymphoma, 2000
Numerous functions have been attributed to CD9 and other members of the transmembrane 4 (TM4) superfamily. CD9 is thought to be involved in cell proliferation, differentiation, motility and survival. It may also function as part of toxin and virus receptor complexes.
S, Hayashi, K, Miyake, P W, Kincade
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Trichoepithelioma with “monster” stromal cells

Journal of Cutaneous Pathology, 2001
Trichoepithelioma is a benign tumor of trichogenic origin which appears predominantly in childhood or in young adults. Different forms have been described according to clinical and histological features. The authors report a unique variant of trichoepithelioma arising on the limb of a 27‐year‐old man.
J, Rivet, C, Rogez, J, Wechsler
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Stromal Cell Responses in Infection

2018
Stromal cells and the immune functions that they regulate underpin multiple aspects of host defence, but the study of stromal cells as targets of infection and as regulators of anti-infective immunity is in its infancy and still limited to a few well-worked examples.
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Immunosuppression by Intestinal Stromal Cells

2018
This chapter summarizes evidence that intestinal myofibroblasts, also called intestinal stromal cells, are derived in the adult from tissue mesenchymal stem cells under homeostasis and may be replenished by bone marrow mesenchymal stromal (stem) cells that are recruited after severe intestinal injury.
Iryna V, Pinchuk, Don W, Powell
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Hemangioblastoma stromal cells

Diagnostic Cytopathology, 2015
José A, Jiménez-Heffernan, Carmen, Bárcena, María, Pascual-Gallego, José M, Cañizal   +3 more
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Marrow stromal stem cells

Journal of Cell Science, 1988
ABSTRACT Evidence for the hypothesis that there are stromal stem cells present in the soft connective tissues associated with marrow and bone surfaces that are able to give rise to a number of different cell lines is reviewed. The lines are currently designated fibroblastic, reticular, adipocytic and osteogenic.
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