Tumor‐Infiltrating mregDCs Restrain Anti‐Tumor Immunity in Early Relapse HCC
Tumor‐infiltrating mregDCs are regulated by the TNFR2‐non‐canonical NF‐κB axis, which is mediated by TNF‐α secreted by CD161+CD8+ T cells. These mregDCs recruit CD161+CD8+ T cells via the CCL20‐CCR6 axis, forming a positive feedback loop that enhances immunosuppression, promotes early recurrence of HCC, and further confirms TNFR2 as a key therapeutic ...
Zefan Zhang +13 more
wiley +1 more source
MarginPath is a novel vision‐language system that automates breast cancer margin assessment using a single label‐free multiphoton microscopy image. By integrating tumor‐associated collagen signatures with virtual H&E imaging, it generates accurate margin heatmaps and comprehensive diagnostic reports.
Shu Wang +15 more
wiley +1 more source
Active Microrheology Reveals Distinct ECM Mechanical Signatures Induced by Stromal Cells of Different Tissue Origins during Vascular Morphogenesis. [PDF]
Lanterman M +3 more
europepmc +1 more source
Instant fluorescence lifetime imaging microscopy reveals mechano-metabolic reprogramming of stromal cells in breast peritumor microenvironment. [PDF]
Najera J +7 more
europepmc +1 more source
Proliferation, Adhesion, and Morphology of Bone-Derived Stromal Cells on Xenogenic Collagen Matrices: An In Vitro Study. [PDF]
Brunello G +6 more
europepmc +1 more source
In vitro assays for investigating the immunomodulatory properties of human mesenchymal stromal cells. [PDF]
Lethager LL +7 more
europepmc +1 more source
Dynamic Reprogramming of PDGFRA-Expressing Stromal Cells Facilitates WNT-Driven Transformation by Promoting a Fetal-Like State in the Intestinal Epithelium. [PDF]
Pellon-Cardenas O +25 more
europepmc +1 more source
Enhanced Human Antigen-Specific B Cell Responses Using In Vitro 3D Tonsil Cultures Containing Stromal Cells. [PDF]
Braham MVJ +11 more
europepmc +1 more source

