Results 21 to 30 of about 604,769 (337)

Failure of intravenous or intracardiac delivery of mesenchymal stromal cells to improve outcomes after focal traumatic brain injury in the female rat. [PDF]

PLoS ONE, 2015
Mesenchymal stromal cells secrete a variety of anti-inflammatory factors and may provide a regenerative medicine option for the treatment of traumatic brain injury.
L Christine Turtzo, Matthew D Budde, Dana D Dean, Eric M Gold, Bobbi K Lewis, Lindsay Janes, Jacob Lescher, Tiziana Coppola, Angela Yarnell, Neil E Grunberg, Joseph A Frank   +10 more
doaj   +1 more source

Tumor-associated Endo180 requires stromal-derived LOX to promote metastatic prostate cancer cell migration on human ECM surfaces [PDF]

, 2015
The diverse composition and structure of extracellular matrix (ECM) interfaces encountered by tumor cells at secondary tissue sites can influence metastatic progression. Extensive in vitro and in vivo data has confirmed that metastasizing tumor cells can
Caley, Matthew P., Gronau, Julian H., King, Helen, Rodriguez-Teja, Mercedes, Shah, Neel, Sturge, Justin, Wang, Kai, Waxman, Jonathan   +7 more
core   +2 more sources

Isolation of human bone marrow stromal cells from bone marrow biopsies for single-cell RNA sequencing

STAR Protocols, 2021
Summary: Bone marrow (BM) mesenchymal stromal cells play an important role in regulating stem cell quiescence and homeostasis; they are also key contributors to various hematological malignancies. However, human bone marrow stromal cells are difficult to
Hélène F.E. Gleitz, Inge A.M. Snoeren, Stijn N.R. Fuchs, Nils B. Leimkühler, Rebekka K. Schneider   +4 more
doaj   +1 more source

Stromal cell-associated erythropoiesis [PDF]

Blood, 1986
Abstract A novel cover slip-transfer culture system was designed to study the functional roles of stromal cells in hemopoiesis, particularly erythropoiesis. Human bone marrow stromal cell colonies were allowed to develop on small glass cover slips in liquid medium.
S, Tsai, C A, Sieff, D G, Nathan
openaire   +3 more sources

CD271 antigen defines a subset of multipotent stromal cells with immunosuppressive and lymphohematopoietic engraftment-promoting properties

Haematologica, 2010
Background In vitro proliferative and differentiation potential of mesenchymal stromal cells generated from CD271+ bone marrow mononuclear cells (CD271-mesenchymal stromal cells) has been demonstrated in several earlier and recent reports. In the present
Selim Kuçi, Zyrafete Kuçi, Hermann Kreyenberg, Erika Deak, Kathrin Pütsch, Sabine Huenecke, Chandrasekhar Amara, Stefanie Koller, Eva Rettinger, Manuel Grez, Ulrike Koehl, Hatixhe Latifi-Pupovci, Reinhard Henschler, Torsten Tonn, Dorothee von Laer, Thomas Klingebiel, Peter Bader   +16 more
doaj   +1 more source

Mesenchymal Differentiation and Organ Distribution of Established Human Stromal Cell Lines in NOD/SCID Mice [PDF]

, 2001
Two human stromal cell lines were established previously from bone marrow-derived primary long-term cultures by immortalization using the SV40 large T antigen and cellular cloning. After irradiation, the fibroblast-like cell lines L87/4 and L88/5 support
Huss, Ralf, Meissner, Petra, Moosmann, Sabine, Sagebiel, Sabine, Thalmeier, Karin, Wiest, Irmgard   +5 more
core   +1 more source

Bovine endometrial stromal cells display osteogenic properties

Reproductive Biology and Endocrinology, 2008
The endometrium is central to mammalian fertility. The endometrial stromal cells are very dynamic, growing and differentiating throughout the estrous cycle and pregnancy.
Cavirani Sandro, Capocefalo Antonio, Franceschi Valentina, Donofrio Gaetano, Sheldon Iain   +4 more
doaj   +1 more source

Marrow stromal stem cells [PDF]

Journal of Clinical Investigation, 2000
Multipotential marrow stromal stem cells were known as early as 1968 (1) through the work of Friedenstein and his coworkers, who established that cells that are adherent, clonogenic, nonphagocytic, and fibroblastic in habit (defined as colony-forming units–fibroblastic; CFU-Fs) can be isolated from the bone marrow stroma of postnatal organisms. CFU-Fs,
BIANCO, Paolo, Pamela Gehron Robey
openaire   +2 more sources

Multipotent mesenchymal stromal cells from amniotic fluid: solid perspectives for clinical application

Haematologica, 2008
Background Mesenchymal stromal cells are multipotent cells considered to be of great promise for use in regenerative medicine. However, the cell dose may be a critical factor in many clinical conditions and the yield resulting from the ex vivo expansion ...
Nadia Sessarego, Alessia Parodi, Marina Podestà, Federica Benvenuto, Massimo Mogni, Valentina Raviolo, Mario Lituania, Annalisa Kunkl, Guido Ferlazzo, Franca Dagna Bricarelli, Antonio Uccelli, Francesco Frassoni   +11 more
doaj   +1 more source

SerpinB2 regulates stromal remodelling and local invasion in pancreatic cancer [PDF]

, 2017
Pancreatic cancer has a devastating prognosis, with an overall 5-year survival rate of ~8%, restricted treatment options and characteristic molecular heterogeneity.
A H Allam, A Neesse, A Neesse, A V Biankin, A Xue, AB Seymour, AD Rhim, AK Witkiewicz, AM LeBeau, AR Shekouh, AV Biankin, B Hinz, BC Ozdemir, BJ Cochran, BJ Cochran, C Gaggioli, C Vennin, D Croucher, D Goldstein, D Herrmann, D Herrmann, D Mahadevan, D N Saunders, D Telgenhoff, DD Von Hoff, DR Croucher, DR Croucher, E Cerami, F Al-Ejeh, G Finak, H Shiomi, HW Smith, I Garrido-Laguna, J Condeelis, J Gao, J Gore, J Lee, J Li, J P Morton, J R W Conway, JA Lee, JJ Lee, JP Morton, K Kessenbrock, K L Vine, L Harris, M C Lucas, M J Cowley, M Nobis, M Pajic, M Pinese, M Ranson, MJ Duffy, ML Nyström, N L E Harris, N Waddell, P Bailey, P Carmeliet, P Timpson, P Timpson, R Cicchi, R F Shearer, R Kalluri, R Smith, RF Shearer, RG Rowe, RL Siegel, S Nurmenniemi, S Ulisse, SC Barry, SR Hingorani, SR Hingorani, TK Stutchbury, WA Schroder, Y Takeuchi, ZS Boyd, Ö Babur   +76 more
core   +1 more source