Results 11 to 20 of about 252,361 (259)
Gastrointestinal stromal tumor [PDF]
Background GISTs are a subset of mesenchymal tumors and represent the most common mesenchymal neoplasms of GI tract. However, GIST is a recently recognized tumor entity and the literature on these stromal tumors has rapidly expanded. Methods An extensive
Levidou Georgia +6 more
doaj +4 more sources
Gastrointestinal Stromal Tumors [PDF]
GI stromal tumors (GISTs) are neoplasms with a varying malignancy potential ranging from virtually indolent tumors to rapidly progressing cancers. GISTs occur throughout the intestinal tract, and most harbor an activating mutation in either KIT or platelet-derived growth factor A ( PDGFRA).
Hohenberger P +3 more
+10 more sources
[Gastrointestinal stromal tumors]. [PDF]
Gastrointestinal stromal tumor (GIST) account for 1% of all gastrointestinal neoplasms and are the most common mesenchymal tumor of gastrointestinal tract. There are considered to originate fom the intestinal cell of Cajal, an intestinal pacemaker cell, characterized usually express the KIT protein on immunohistochemistry.
Ridolfini, Mp +7 more
+11 more sources
Gastrointestinal stromal tumors [PDF]
Gastrointestinal stromal tumors (GISTs) are mesenchymal gut tumors that differ dramatically from other histologically similar neoplasms, such as leimomyomas, leiomyosarcomas (LMS), and neural tumors. Complete surgical removal remains the best current therapy for GISTs, but even major resections are associated with recurrence in approximately 90% of ...
C D, Blanke +2 more
openaire +4 more sources
Gastrointestinal Stromal Tumors [PDF]
Gastrointestinal stromal tumors (GISTs) are the most common mesenchymal tumor of the gastrointestinal tract. Soon after GIST was recognized as a tumor driven by a KIT or platelet-derived growth factor receptor mutation, it became the first solid tumor target for tyrosine kinase inhibitor therapies.
Markku, Miettinen, Jerzy, Lasota
openaire +2 more sources
The tumor immune microenvironment significantly affects tumor progression, metastasis, and clinical therapy. Its basic cell components include tumor-associated endothelial cells, fibroblasts, and macrophages, all of which constitute the tumor stroma and ...
Changcan Li +7 more
doaj +1 more source
Stromal CD10 expression in invasive breast carcinoma [PDF]
Background and Objective: This study aimed to assess the immunohistochemical expression of stromal CD10 in invasive breast carcinoma and determine its relationship with some clinicopathological parameters.
Haval D. Ali +3 more
doaj +1 more source
After more than a decade of controversy on the role of stromal cells in the tumor microenvironment, the emerging data shed light on pro-tumorigenic and potential anti-cancer factors, as well as on the roots of the discrepancies.
Armel H. Nwabo Kamdje +5 more
doaj +1 more source
Rectal stromal tumor with an exceptional liver and bone metastatic locations
Gastrointestinal stromal tumours (GIST) are rare mesenchymal tumours which represent 1% to 3% of gastrointestinal neoplasm. Rectal location of GIST is extremely rare reaching 5% of GIST and only 0.1% of rectal tumours.
Dougaz Mohamed Wejih +5 more
doaj +1 more source

