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Gastrointestinal stromal tumor [PDF]
World Journal of Surgical Oncology, 2009 Background GISTs are a subset of mesenchymal tumors and represent the most common mesenchymal neoplasms of GI tract. However, GIST is a recently recognized tumor entity and the literature on these stromal tumors has rapidly expanded. Methods An extensive
Levidou Georgia +6 more
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Gastrointestinal Stromal Tumors [PDF]
Visceral Medicine, 2018 GI stromal tumors (GISTs) are neoplasms with a varying malignancy potential ranging from virtually indolent tumors to rapidly progressing cancers. GISTs occur throughout the intestinal tract, and most harbor an activating mutation in either KIT or platelet-derived growth factor A ( PDGFRA).
Hohenberger P +3 more
+10 more sources
Gastrointestinal stromal tumors [PDF]
Current Treatment Options in Oncology, 2001 Gastrointestinal stromal tumors (GISTs) are mesenchymal gut tumors that differ dramatically from other histologically similar neoplasms, such as leimomyomas, leiomyosarcomas (LMS), and neural tumors. Complete surgical removal remains the best current therapy for GISTs, but even major resections are associated with recurrence in approximately 90% of ...
C D, Blanke +2 more
openaire +4 more sources
Macrophage – tumor cell interaction beyond cytokines
Frontiers in Oncology, 2023 Tumor cells communication with tumor associated macrophages is a highly important factor of tumor malignant potential development. For a long time, studies of this interaction were focused on a cytokine- and other soluble factors -mediated processes ...
Olga Kovaleva +6 more
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A case of primary gastrointestinal stromal tumor of the liver
Radiology Case Reports, 2023 A gastrointestinal stromal tumor (GIST) is the most common mesenchymal tumor of the gastrointestinal tract. The tumor originates from Cajal cells, which generated peristaltic motion.
An Nguyen Thi My Xuan, MD +5 more
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A Paradoxical Effect of Interleukin-32 Isoforms on Cancer
Frontiers in Immunology, 2022 IL-32 plays a contradictory role such as tumor proliferation or suppressor in cancer development depending on the cancer type. In most cancers, it was found that the high expression of IL-32 was associated with more proliferative and progression of ...
Saerok Shim +17 more
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[Gastrointestinal stromal tumors]. [PDF]
Annali italiani di chirurgia, 2011 Gastrointestinal stromal tumor (GIST) account for 1% of all gastrointestinal neoplasms and are the most common mesenchymal tumor of gastrointestinal tract. There are considered to originate fom the intestinal cell of Cajal, an intestinal pacemaker cell, characterized usually express the KIT protein on immunohistochemistry.
Ridolfini, Mp +7 more
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Epithelioid Gastrointestinal Stromal Tumor of Duodenum Mimicking Adenocarcinoma: A Case Report
Journal of Nepal Medical Association, 2021 Gastrointestinal stromal tumor is a mesenchymal tumor of gastro-intestinal tract. This epithelioid type gastrointestinal stromal tumor seen in a 22-year-old male with epigastric pain as a presenting symptom had morphological resemblance to carcinoma ...
Sansar Babu Tiwari, Shovana Karki
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Stromal cells in the tumor microenvironment: accomplices of tumor progression?
Cell Death and Disease, 2023 The tumor microenvironment (TME) is made up of cells and extracellular matrix (non-cellular component), and cellular components include cancer cells and non-malignant cells such as immune cells and stromal cells.
Yan Zhao +9 more
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