Results 61 to 70 of about 662,923 (221)
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Movement in workplace environments – configurational or programmed? [PDF]
, 2007 In countless case studies space syntax research has found that the configuration of a spatial system offers a powerful explanation to movement flows.
Sailer, K.
core
Cosmological gravitomagnetism and Mach's principle
, 2006 The spin axes of gyroscopes experimentally define local non-rotating frames. But what physical cause governs the time-evolution of gyroscope axes? We consider linear perturbations of Friedmann-Robertson-Walker cosmologies with k=0.
A. Einstein +15 more
core +1 more source
Molecular Oncology, EarlyView.A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira +14 more
wiley +1 more source
Fire, 2019 Despite major advances in numerical weather prediction, few resources exist to forecast wildland fire danger conditions to support operational fire management decisions and community early-warning systems.
W. Matt Jolly +3 more
doaj +1 more source
On the metric operator for the imaginary cubic oscillator
, 2012 We show that the eigenvectors of the PT-symmetric imaginary cubic oscillator are complete, but do not form a Riesz basis. This results in the existence of a bounded metric operator having intrinsic singularity reflected in the inevitable unboundedness of
Krejcirik, David, Siegl, Petr
core +1 more source
Molecular Oncology, EarlyView.This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian +10 more
wiley +1 more source
A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression
Molecular Oncology, EarlyView.Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak +8 more
wiley +1 more source
Asthma 101 for Schools: Successes and Challenges in Transitioning to Online Delivery
Frontiers in Public Health, 2016 Florida Asthma Program (FAP) staff worked with evaluators from the Florida State University College of Medicine (FSU) to assess participation and quality of the American Lung Association’s (ALA) Asthma 101 asthma management education program for school ...
Alexandra Catherine Hayes Nowakowski +3 more
doaj +1 more source