Results 61 to 70 of about 6,691,628 (330)

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

open access: yesFEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Structural Constraints in Postsecondary Education: Capacity and Financial Aid [PDF]

open access: yes, 2006
Includes presentation materials on advocacy options to help increase public higher education capacity and secure financial aid for low-income students in order to meet increasing demand as high school graduation rates rise as a result of ...

core  

Interface Problems: Structural Constraints on Interpretation? [PDF]

open access: yesJournal of Psycholinguistic Research, 2005
Five experiments investigated the interpretation of quantified noun phrases in relation to discourse structure. They demonstrated, using questionnaire and on-line reading techniques, that readers in English prefer to give a quantified noun phrase in (VP-external) subject position a presuppositional interpretation, in which the noun phrase limits or ...
Frazier, Lyn   +5 more
openaire   +2 more sources

Function‐driven design of a surrogate interleukin‐2 receptor ligand

open access: yesFEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang   +9 more
wiley   +1 more source

Conference Report: Teaching Against the Grain: The Challenges of Teaching Qualitative Research in the Health Sciences. A National Workshop on Teaching Qualitative Research in the Health Sciences

open access: yesForum: Qualitative Social Research, 2005
This essay reflects on the proceedings of an invitational workshop on the nature and challenges of teaching qualitative research (QR) in health science settings. The context of this workshop is the increasing interest in QR in the health sciences and the
Joan M. Eakin, Eric Mykhalovskiy
doaj  

(De)Constructing Conflict: A Focused Review of War and Peace Journalism [PDF]

open access: yesConflict & Communication Online, 2006
This overview of the media and conflict literature and case study of media coverage of peace offers a framework and guidance for peace journalism. Many studies show media rarely report conflict neutrally.
Susan Dente Ross
doaj  

CONCEPTUAL ASPECTS AND APPLIED MEANS OF STRUCTURAL TRANSFORMATIONS OF THE RUSSIAN ECONOMY IN TERMS OF EXTERNAL CONSTRAINTS

open access: yesВестник университета, 2020
The theoretical and economic study of various aspects of the impact of external restrictions on the Russian economy in recent years has become one of the actively developing areas of scientific research.
V. M. Vazagov, M. B. Miroshnichenko
doaj   +1 more source

The Search for the American Dream:Interpersonal, Cultural, and Structural Constraints on Immigrants [PDF]

open access: yes, 2020
The American Dream is a goal sought out by many people from around the globe. But immigrants must overcome many barriers that may inhibit that dream.
Smith, Milenna
core   +1 more source

P-N learning: Bootstrapping binary classifiers by structural constraints

open access: yes2010 IEEE Computer Society Conference on Computer Vision and Pattern Recognition, 2010
This paper shows that the performance of a binary classifier can be significantly improved by the processing of structured unlabeled data, i.e. data are structured if knowing the label of one example restricts the labeling of the others.
Zdenek Kalal, Jiri Matas, K. Mikolajczyk
semanticscholar   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Home - About - Disclaimer - Privacy