Results 121 to 130 of about 622,519 (292)

Autophagosome marker, LC3, is released extracellularly via several distinct pathways

FEBS Open Bio, EarlyView.
This study establishes a novel HiBiT‐tagging system for ultrasensitive detection of LC3, revealing multiple pathways for its extracellular secretion. It demonstrates that LC3 is released via both autophagy‐dependent and ‐independent mechanisms, including a novel route for nonlipidated LC3‐I.
Koki Saito, Masashi Arakawa, Koki Maeda, Eiji Morita   +3 more
wiley   +1 more source

Computational Material Analysis of Structural and Hemodynamic Model of Coronary Stent by CFD/FEA in Computer Aided Mechanical Engineering Approach

, 2016
Ö. Karaçal
openalex   +1 more source

Analysis of Treacher Collins syndrome 4‐associated mutations in Schizosaccharomyces pombe

FEBS Open Bio, EarlyView.
Fission yeast models carrying Treacher Collins syndrome type 4‐associated mutations reveal that impaired processivity of RNA polymerase I leads to defective rRNA transcription. This study highlights the essential role of a conserved arginine residue in Pol I elongation and provides mechanistic insight into the pathogenesis of ribosomopathies.
Kei Kawakami, Hiroaki Kato
wiley   +1 more source

Synergistic Structural and Defect Engineering in MoS ₂ Featuring Ultra‐Expanded Interlayers for Fast‐Chargeable and Long‐Durable Sodium‐Ion Batteries [PDF]

Zhefei Sun, Jie Zhang, Jiaming Zhang, Chao Zhang, Jiajia Han, Zhiyi Sun, Huiping Yang, Jianhai Pan, Xiaoyu Wu, Shijie Feng, Hui Ying Yang, Wenxing Chen, Li Zhang, Dong‐Liang Peng, Qiaobao Zhang   +14 more
openalex   +1 more source

DDX3X induces mesenchymal transition of endothelial cells by disrupting BMPR2 signaling

FEBS Open Bio, EarlyView.
Elevated DDX3X expression led to downregulation of BMPR2, a key regulator of endothelial homeostasis and function. Our co‐immunoprecipitation assays further demonstrated a molecular interaction between DDX3X and BMPR2. Notably, DDX3X promoted lysosomal degradation of BMPR2, thereby impairing its downstream signaling and facilitating endothelial‐to ...
Yu Zhang, Jing Wang, De‐Hui Qian, Yang‐Fan Lv, Tian‐Le Cheng, Da‐Peng Wang, Jing Zhang, Ye Fan   +7 more
wiley   +1 more source

Design for Robustness: Bio-Inspired Perspectives in Structural Engineering. [PDF]

Biomimetics (Basel), 2023
Kiakojouri F, De Biagi V, Abbracciavento L.   +2 more
europepmc   +1 more source

Structural engineer to structural engineer: conversation with Steve Johnston [PDF]

The Structural Design of Tall Buildings, 2001
Chris D. Poland, James O. Malley
openaire   +1 more source

Overview of technical research on safety monitoring, early warning, and risk assessment for underground structural engineering construction

, 2023
Zheng Wan, Qin Jie, Zhaobin Wei
openalex   +1 more source

Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276

FEBS Open Bio, EarlyView.
Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig, Swanhild Lohse, Sara Elahi, Nils Hartmann, Stefanie Deckert, Shutian Si, Alexander Desuki, Anja Harder   +7 more
wiley   +1 more source

Structural Engineering [PDF]

, 1994
openaire   +1 more source