Results 51 to 60 of about 1,885,843 (350)

The immunological interface: dendritic cells as key regulators in metabolic dysfunction‐associated steatotic liver disease

open access: yesFEBS Letters, EarlyView.
Metabolic dysfunction‐associated steatotic liver disease (MASLD) affects nearly one‐third of the global population and poses a significant risk of progression to cirrhosis or liver cancer. Here, we discuss the roles of hepatic dendritic cell subtypes in MASLD, highlighting their distinct contributions to disease initiation and progression, and their ...
Camilla Klaimi   +3 more
wiley   +1 more source

Designing by Geometry. Rankine's Theorems of Transformation of Structures. [PDF]

open access: yes, 2010
William John Macquorn Rankine (1820-1872) was one of the main figures in establishing engineering science in the second half of the 19th. Century. His Manual of Applied Mechanics (1858) gathers most of his contributions to strength of materials and ...
Huerta Fernández, Santiago
core   +1 more source

Transfer of Individual Micro- and Nanoparticles for High- Precision 3D Analysis Using 360° Electron Tomography [PDF]

open access: yes, 2018
A versatile approach is demonstrated, providing a general routine for an extensive and advanced 3D characterization of individually selected micro- and nanoparticles, enabling the combination of complementary and scale-bridging techniques ...
Aert   +55 more
core   +1 more source

Self-cyclisation as a general and efficient platform for peptide and protein macrocyclisation

open access: yesbioRxiv, 2022
Head-to-tail macrocyclization of proteins and peptides can increase their structural stability, however, potential polymerization can lead to reduced yields.
Xinying Jia   +10 more
semanticscholar   +1 more source

The power of microRNA regulation—insights into immunity and metabolism

open access: yesFEBS Letters, EarlyView.
MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto   +2 more
wiley   +1 more source

A Finite Element‑Based Methodology for the Thermo‑mechanical Analysis of Early Age Behavior in Concrete Structures [PDF]

open access: yes, 2019
This paper presents a general procedure based on fracture mechanics models in order to analyze the level of cracking and structural safety in reinforced concrete elements at early ages, depending on the stripping time.
Cabezas, Joaquín   +4 more
core   +3 more sources

ON THE THREAT OF SUPPLIERS FOR THE ENGINEERING CONSULTING AND DESIGN SERVICES FIRMS [PDF]

open access: yesRisk in Contemporary Economy, 2014
In the case of companies from engineering consulting and design services industry the classic models of analysis (e.g. Porter's five forces for structural analysis) exhibit interesting aspects in comparison with the situation when applied to traditional ...
Gabriel Sorin STROE
doaj  

Design revisions of complex building structures: work experience in Lithuania, legislative, organizational and technical aspects

open access: yesEngineering Structures and Technologies, 2015
This paper presents an engineering survey based on experience of the authors during design and expertise of complex building structures in period of 2000–2014.
Michail Samofalov, Vytautas Papinigis
doaj   +1 more source

A stepwise emergence of evolution in the RNA world

open access: yesFEBS Letters, EarlyView.
How did biological evolution emerge from chemical reactions? This perspective proposes a gradual scenario of self‐organization among RNA molecules, where catalytic feedback on random mixtures plays the central role. Short oligomers cross‐ligate, and self‐assembly enables heritable variations. An event of template‐externalization marks the transition to
Philippe Nghe
wiley   +1 more source

New Approach to Nonlinear Dynamic Analysis of Reinforced Concrete 3D Frames; An Accurate and Computational Efficient Mathematical Model

open access: yesApplied Sciences, 2022
The structural engineering community often deals with the issue of inelastic incursions of the structural response. Although buildings situated in seismic regions are usually designed using elastic analysis, most encounter significant inelastic ...
Ruben Iacob Munteanu   +3 more
doaj   +1 more source

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