Results 91 to 100 of about 1,128,803 (283)

Payload shrouds structural optimization study Final report [PDF]

open access: yes
Computer programs for synthesizing structural arrangements for ring-stiffened, honeycomb sandwich, and ring-stringer stiffened methods of construction for Saturn nose ...
Hendrix, E. S.
core   +1 more source

Analog Multiple Descriptions: A Zero-Delay Source-Channel Coding Approach

open access: yes, 2015
This paper extends the well-known source coding problem of multiple descriptions, in its general and basic setting, to analog source-channel coding scenarios.
Akyol, Emrah   +2 more
core   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

open access: yesMolecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang   +3 more
wiley   +1 more source

Structural optimization by generalized, multilevel decomposition [PDF]

open access: yes
The developments toward a general multilevel optimization capability and results for a three-level structural optimization are described. The method partitions a structure into a number of substructuring levels where each substructure corresponds to a ...
James, B. B.   +2 more
core   +1 more source

Structural optimization with $\tt{FreeFem++}$

open access: yesStructural and Multidisciplinary Optimization, 2006
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Allaire, Grégoire, Pantz, Olivier
openaire   +2 more sources

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

Industrial-grade carbon fiber reinforced epoxy vitrimer composites: Reprocessing, repairing and recycling

open access: yesAdvanced Industrial and Engineering Polymer Research
Carbon fiber reinforced thermoset composites (CFRP) have demonstrated significant potential for industrial applications. However, their permanent cross-linked networks pose challenges for reprocessing, repairing, and recycling.
Mei Fang   +6 more
doaj   +1 more source

Structural model optimization using statistical evaluation [PDF]

open access: yes
The results of research in applying statistical methods to the problem of structural dynamic system identification are presented. The study is in three parts: a review of previous approaches by other researchers, a development of various linear ...
Collins, J. D.   +3 more
core   +1 more source

Interface‐Filtering Structural Optimization

open access: yesInternational Journal for Numerical Methods in Engineering
ABSTRACTIn this paper, we present an interface‐filtering structural optimization method that optimizes structural shape and topology through successive interface movements. This interface filtering is achieved via the combination of the variable‐radius‐based partial‐differential‐equation (PDE) filtering and the Heaviside projection on a density ...
Tianye Wang, Xiaoping Qian
openaire   +2 more sources

Targeting p38α in cancer: challenges, opportunities, and emerging strategies

open access: yesMolecular Oncology, EarlyView.
p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley   +1 more source

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