Results 91 to 100 of about 201,361 (344)
In Defense of Realism and Selectivism from Lyons’s Objections [PDF]
, 2019 Lyons (2016, 2017, 2018) formulates Laudan’s (1981) historical objection to scientific realism as a modus tollens. I present a better formulation of Laudan’s objection, and then argue that Lyons’s formulation is supererogatory.
Park, Seungbae
core +2 more sources
Molecular Oncology, EarlyView.Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié +13 more
wiley +1 more source
Generating realistic scaled complex networks [PDF]
, 2017 Research on generative models is a central project in the emerging field of network science, and it studies how statistical patterns found in real networks could be generated by formal rules.
Gutfraind, Alexander +4 more
core +3 more sources
Molecular Oncology, EarlyView.The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source
Familiar faces rendered strange: Why inconsistent realism drives characters into the uncanny valley [PDF]
, 2016 Computer-modeled characters resembling real people sometimes elicit cold, eerie feelings. This effect, called the uncanny valley, has been attributed to uncertainty about whether the character is human or living or real.
Chattopadhyay, Debaleena +1 more
core +2 more sources
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Scientific Realism and High Energy Physics [PDF]
, 2017 The paper discusses major implications of high energy physics for the scientific realism debate. The first part analyses the ways in which aspects of the empirically well-confirmed standard model of particle physics are relevant for a reassessment of ...
Dawid, Richard
core
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
The reality of relations [PDF]
, 2017 Discussing the contemporary debate about the metaphysics of relations and structural realism, I analyse the philosophical significance of relational quantum mechanics (RQM).
Candiotto, Laura
core
Situating organizational action: the relational sociology of organizations [PDF]
, 2006 This paper advances a relational sociology of organization that seeks to address concerns over how organizational action is understood and situated.
Delbridge, R, Mutch, A, Ventresca, M
core +1 more source