Results 61 to 70 of about 338,804 (265)

Determining Parental Factors for Clinical Trial Attrition in Pediatric Acute Lymphoblastic Leukemia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background/Objectives Despite high enrollment rates on Children's Oncology Group (COG) protocols, attrition after initial consent is challenging, introducing bias and prolonging trial completion. While adult oncology literature has identified predictors of withdrawal, little is known about caregiver decision‐making for child participation in ...
Kimberly L. Stathas, Jakob Q. Weiss, Kellee N. Parker, Cathy Lee‐Miller   +3 more
wiley   +1 more source

Whole-genome sequencing reveals rare and structural variants contributing to psoriasis and identifies CERCAM as a risk gene

Cell Genomics
Summary: Psoriasis vulgaris (PsV) is an immune-mediated inflammatory skin disorder with complex genetic architecture. Most genome-wide association studies (GWASs) of PsV have been limited to analyzing common single-nucleotide variants in Europeans ...
Kyuto Sonehara, Rei Watanabe, Yutaka Matsumura, Yuichi Mitsui, Yosuke Ogawa, Kaori Odomari, Saori Sakaue, Shinichi Namba, Mariko Komuro, Mio Edamoto, Junya Watanabe, Tomomitsu Hirota, Noriko Arase, Yuumi Nakamura, Kimiko Nakajima, Takashi Okamoto, Rika Nishikawa, Kenichi Yamamoto, Ken Suzuki, Toshihiro Kishikawa, Ryuya Edahiro, Yuya Shirai, Tatsuhiko Naito, Noah Sasa, Yosuke Ishitsuka, Junichi Furuta, Kayo Kunimoto, Ikko Kajihara, Satoshi Fukushima, Hideaki Miyachi, Hiroyuki Matsue, Masahiro Kamata, Mami Momose, Ippei Miyagawa, Hiroaki Tanaka, Masanobu Ueno, Toshinori Bito, Hiroshi Nagai, Tetsuya Ikeda, Tatsuya Horikawa, Atsuko Adachi, Tsukasa Matsubara, Emi Nishida, Koichi Matsuda, Nobuhiro Shojima, Ikuma Nakagawa, Yoshihide Asano, Shinichi Sato, Shinichi Imafuku, Yayoi Tada, Chikako Nishigori, Masatoshi Jinnin, Hironobu Ihn, Akihiko Asahina, Hidehisa Saeki, Toshimasa Yamauchi, Takashi Kadowaki, Tatsuyoshi Kawamura, Shinji Shimada, Ichiro Katayama, Koichiro Higasa, Emiko Noguchi, Shigetoshi Sano, Yoshiya Tanaka, Fumihiko Matsuda, Atsushi Kumanogoh, Mayumi Tamari, Takashi Satoh, Manabu Fujimoto, Akimichi Morita, Yukinori Okada   +70 more
doaj   +1 more source

Structural Analysis of the SARS-CoV-2 Omicron Variant Proteins

Research, 2021
The spread of the latest SARS-CoV-2 variant Omicron is particularly concerning because of the large number of mutations present in its genome and lack of knowledge about how these mutations would affect the current SARS-CoV-2 vaccines and treatments ...
Qiangzhen Yang, Ali Alamdar Shah Syed, Aamir Fahira, Yongyong Shi   +3 more
doaj   +1 more source

Evaluating the Readability of Patient‐Facing Online Educational Materials for Pediatric Leukemia and Lymphoma

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Together, leukemia and lymphoma account for 38.7% of newly diagnosed pediatric cancer cases in the United States each year. Many caregivers utilize online resources to inform medical health decisions. Understanding the readability of these materials is critical to ensuring comprehensible patient education.
Chloe Strege, Simone Intriago Tito, Courtney Popp, William C. Miller, Cindy Eide, Christen Ebens, Jakub Tolar   +6 more
wiley   +1 more source

Individual Genomic Distinctness of Rice Germplasm as Measured with an Average Pairwise Dissimilarity of Genome-Wide SNPs and Structural Variants

Plants
The average pairwise dissimilarity (APD) between one plant sample and other assayed samples based on genetic markers was developed in 2006 to assess genetic distinctness and genetic redundancy in a plant germplasm collection.
Yong-Bi Fu
doaj   +1 more source

Impact of Japan's 2024 Physician Work‐Style Reform on Pediatric Hematology–Oncology: Educational Implications in a 2‐Year Survey

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Japan's 2024 physician work‐style reform introduced legally binding limits on physicians’ working hours, but its impact on education and workforce sustainability in pediatric hematology–oncology (PHO) remains unclear. Procedure We conducted a repeated cross‐sectional study with structured quantitative items and free‐text responses ...
Kiyohiko Kaizu, Masaharu Akiyama, Toshikazu Itabashi, Jun Hayakawa, Takahiro Kikuchi, Ryohei Fukunaga, Katsuyoshi Koh, Takahiro Ueda   +7 more
wiley   +1 more source

Unveiling genomic rearrangements in engineered iPSC lines by optical genome mapping

Molecular Therapy: Methods & Clinical Development
We demonstrate here the use of optical genome mapping (OGM) to detect genetic alterations arising from gene editing by various technologies in human induced pluripotent stem cells (iPSCs).
Darren Finlay, Pooja Hor, Benjamin H. Goldenson, Xiao-Hua Li, Rabi Murad, Dan S. Kaufman, Kristiina Vuori   +6 more
doaj   +1 more source

A Bibliometric Analysis of Publications in Uremic Toxins From 1991 to 2024

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Uremic toxins are a growing area of research in nephrology, with significant implications in the progression and treatment of chronic kidney disease (CKD) and the management of end‐stage kidney disease (ESKD). This bibliometric analysis aims to evaluate the global research trends, key contributors, and the impact of publications in ...
Yuh‐Shan Ho, Karim M. Soliman, Wisit Cheungpasitporn, Wannasit Wathanavasin, Ahmed Daoud, Ahmed I. Kamal, Balázs Szamosfalvi, Tibor Fülöp   +7 more
wiley   +1 more source

The Future of Pediatric Hematology‐Oncology Fellowship Training: Reflections on the American Board of Pediatrics Training Model

Pediatric Blood &Cancer, EarlyView.
Scott C. Borinstein, Scott Moerdler, Alexander A. Boucher, Stacy L. Cooper, Rachel A Egler, Erika Friehling, Richard Ho, Catherine McGuinn, Kathryn S. Sutton, Stacey G. Zahler, Leslie Kersun, Jennifer Kesselheim   +11 more
wiley   +1 more source

Establishing an Apheresis Medicine Program in a Resource‐Constrained Setting: A 5‐Year Experience From Lagos, Nigeria

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Establishing a comprehensive apheresis medicine program in a resource‐constrained setting presents significant structural, financial, and logistical challenges. Despite the growing clinical importance of apheresis services globally, published experience from sub‐Saharan Africa remains sparse.
Folasade Adelekan‐Popoola, Shakirat Gold‐Olufadi, Olufunto Olufela Kalejaiye, Abdullateef Ogala, Rasheed A. Balogun   +4 more
wiley   +1 more source