Results 181 to 190 of about 800,936 (315)

Structural variation drives praziquantel response and host adaptation in <i>Schistosoma japonicum</i>. [PDF]

iScience
Liu Q, Yang K, Zhang W, Xu S, Hu W, Lu Y.   +5 more
europepmc   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Genomic variation in rotaviruses [PDF]

The rotaviruses are a recently defined ubiquitous group of viruses responsible for causing acute-gastroenteritis in human infants and young animals.
Clarke, Ian Nicholas
core  

Corrigendum: Analysis of the structure and trend prediction of China's total health expenditure

Frontiers in Public Health
Hong-yan Li, Rui-xue Zhang
doaj   +1 more source

Flexible and rapid validation of structural variation using adaptive sampling. [PDF]

Eur J Hum Genet
Paivandy A, Lenner F, Eisfeldt J, Jonson T, Ehrencrona H, Lindstrand A, Scherer SW, Feuk L.   +7 more
europepmc   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

The biomedical landscape of genomic structural variation in the qatari population. [PDF]

Nat Commun
Aliyev E, Syed N, Visconti A, Aliyev T, Belkadi A, Ghorbani M, Rossi N, Naeem H, Gandhi GD, Thareja G, Al-Maraghi A, Aamer W, Ibrahim AA, Shaath R, Al-Ajli FO, Razali RM, Sedlazeck FJ, Davila S, Akil A, Suhre K, Mokrab Y, Falchi M, Fakhro KA.   +22 more
europepmc   +1 more source

Establishing an assay to evaluate d‐amino acid oxidase enzyme kinetics and inhibition using WST‐8 redox dye

FEBS Open Bio, EarlyView.
This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake, Yuki Enoki, Yuka Nakazawa, Kazuaki Taguchi, Kazuaki Matsumoto   +4 more
wiley   +1 more source

A simple method to efficiently generate structural variation in plants. [PDF]

PLoS Genet
Bechen LL, Ahsan N, Bahrainwala A, Gehring M, Satyaki PRV.   +4 more
europepmc   +1 more source