Results 201 to 210 of about 15,084,422 (295)

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

FEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss, Ao Li, Eduardo H. Gilglioni, Mayank Bansal, Sumeet Pal Singh, Latifa Bakiri, Alessandra K. Cardozo, Esteban N. Gurzov   +7 more
wiley   +1 more source

Gorilla genome structural variation reveals evolutionary parallelisms with chimpanzee

Structural variation has played an important role in the evolutionary restructuring of human and great ape genomes. Recent analyses have suggested that the genomes of chimpanzee and human have been particularly enriched for this form of genetic variation.
Alkan, Can, Shendure, Jay, Saijadian, Saba, Navarro i Cuartiellas, Arcadi, 1969-, Chen, Lin, Wilson, Richard K., Catacchio, Claudia R., Turner, Emily H., Hormozdiari, Fereydoun, Eichler, Evan E., Archidiacono, Nicoletta, Kidd, Jeffrey M., Malig, Maika, Lee, Choli, Graves, Tina A., Ventura, Mario, Baker, Carl, Marquès i Bonet, Tomàs, 1975-   +17 more
core  

A global map for introgressed structural variation and selection in humans. [PDF]

Science
Hsieh P, Soisangwan N, Gordon DS, Javidh A, Harvey WT, Porubsky D, Hoekzema K, Baker C, Munson KM, Kinipi C, Leavesley M, Brucato N, Cox MP, Ricaut FX, Romero IG, Eichler EE.   +15 more
europepmc   +1 more source

Effect of terahertz irradiation on DNA damage repair in living cells

FEBS Open Bio, EarlyView.
We investigated the effect of terahertz (THz) wave irradiation on DNA double‐strand break (DSB) repair in living cells. We found that THz irradiation enhanced DSB repair at specific frequencies, whereas heat treatment inhibited it, indicating that this effect is nonthermal and frequency‐specific.
Yuya Ueno, Shota Yamazaki, Hiromichi Hoshina, Masahiko Harata   +3 more
wiley   +1 more source

Pangenome-resolved structural variation drives adaptation and trait evolution in cucumber. [PDF]

Nat Genet
Guan J, Li X, Miao H, Yan X, Liu X, Gu X, Visser RGF, Bai Y, Huang S, Zhang Z, Dong S, Zhang S.   +11 more
europepmc   +1 more source

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

FEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana, Avigail Yariv, Tal Oppenheim, Hadar Amartely, Dana Reichmann, Oded Livnah   +5 more
wiley   +1 more source

The landscape of structural variation in pediatric cancer. [PDF]

Cancer Cell
Greenhalgh R, Brady SW, Yang W, Flasch DA, Edmonson MN, Terekhanova NV, Liu Y, Wang J, Szlachta KA, Tian L, Putnam DK, Rahbarinia D, Kolekar P, Zhou X, Gerhard DS, Ma X, Zhang J.   +16 more
europepmc   +1 more source

Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy

FEBS Open Bio, EarlyView.
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan, Ikram A. Burney, Shika Hanif Malgundkar, Siva Ramamoorthy, Ressin Varghese, Mohamed A. Al‐Kindi, Hamad Al Riyami, Shadia Al Bahlani, Sergey Dobretsov, Syed Imran Hassan, Benjamin K. Tsang, Yahya Tamimi   +11 more
wiley   +1 more source

Comparative Chloroplast and Mitochondrial Genomics of <i>Sorbus</i> L. Sensu Lato: Genome Diversity, Structural Variation, and Phylogeny. [PDF]

Int J Mol Sci
Wu Y, Yang W, Zheng Y, Yu X, Zhang C.
europepmc   +1 more source

Exploring the influence of lactoferrin on wound healing and related signaling pathways: a systematic review

FEBS Open Bio, EarlyView.
Lactoferrin promotes wound healing by activating MAPK, PI3K/Akt, and extracellular matrix pathways, enhancing fibroblast remodeling, proliferation, and re‐epithelialization. These mechanisms highlight its therapeutic potential in inflammation control, tissue repair, and remodeling.
Morgana Lüdtke Azevedo, Kátia Cristiane Hall, Matheus dos Santos Fernandez, Geovanna Peter Corrêa, Rafael Guerra Lund   +4 more
wiley   +1 more source