Results 211 to 220 of about 5,946,777 (312)

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

FEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana, Avigail Yariv, Tal Oppenheim, Hadar Amartely, Dana Reichmann, Oded Livnah   +5 more
wiley   +1 more source

Revealing the Shared Genetic Basis of Thermal Adaptation and Abdominal Adiposity in Wenchang Chicken Using Whole-Genome Structural Variation Analysis. [PDF]

Animals (Basel)
Sun Y, Gu L, Chen S, Cai D, Zhou Z, Li J, Sang Z, Wei S, Nie Q, Zhang D.   +9 more
europepmc   +1 more source

Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy

FEBS Open Bio, EarlyView.
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan, Ikram A. Burney, Shika Hanif Malgundkar, Siva Ramamoorthy, Ressin Varghese, Mohamed A. Al‐Kindi, Hamad Al Riyami, Shadia Al Bahlani, Sergey Dobretsov, Syed Imran Hassan, Benjamin K. Tsang, Yahya Tamimi   +11 more
wiley   +1 more source

Exploring the influence of lactoferrin on wound healing and related signaling pathways: a systematic review

FEBS Open Bio, EarlyView.
Lactoferrin promotes wound healing by activating MAPK, PI3K/Akt, and extracellular matrix pathways, enhancing fibroblast remodeling, proliferation, and re‐epithelialization. These mechanisms highlight its therapeutic potential in inflammation control, tissue repair, and remodeling.
Morgana Lüdtke Azevedo, Kátia Cristiane Hall, Matheus dos Santos Fernandez, Geovanna Peter Corrêa, Rafael Guerra Lund   +4 more
wiley   +1 more source

Trace metal ions are strongly associated with the structural variation in vineyard soil microbial communities along altitude gradients. [PDF]

Front Microbiol
Li Y, Bai X, Yu X, Duan B, Li W, Zhang L, Wang J, Yangzong C, Nan L, Liu X.   +9 more
europepmc   +1 more source

Optimizing photoexcitation conditions for time‐resolved X‐ray solution scattering experiments

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering (TR‐XSS) is a powerful technique to visualize how proteins change their structure in real time after light activation. Selecting the right laser photoexcitation conditions—fluence, excitation geometry, and sample refresh rate—is critical to maximize the experimental signal while avoiding unwanted side effects ...
Matteo Levantino
wiley   +1 more source

Analysing Variation in English

This book brings together a range of perspectives on the collection, analysis and broader relevance of variable language data.Cover -- Half-title -- Title -- Copyright -- Contents -- Figures -- Tables -- Contributors -- Abbreviations -- Corpora and tools
McMahon, April., Maguire, Warren.
core  

Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA

FEBS Open Bio, EarlyView.
Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley   +1 more source

Lifespan brain structural variation reveals shared organization across mental health conditions

Hettwer MD, Saberi A, Shafiei G, Manoli A, De Boer AA, Alnæs D, Alonso P, Arango C, Assaf M, Avram M, Balachander S, Banaj N, Başgöze Z, Batistuzzo MC, Bauduin SE, Benedetti F, Bertolin S, Besteher B, Biagi L, Blair RJ, Blair K, Bölte S, Borgwardt S, Bosco P, Brambilla P, Bravi B, Brennan BP, Bruin WB, Busatto GF, Cairns MJ, Calderoni S, Calhoun V, Calvo R, Cano M, Carr VJ, Carruthers SP, Caruana GF, Caseras X, Catts SV, Chi I, Cobia D, Colombo F, Couto MB, Crespo-Facorro B, Cullen KR, Dannlowski U, Dapretto M, Di Martino A, Diefenbach GJ, Dols A, Duran F, Dzinalija N, Ecker C, Ehrlich S, Eng GK, Fair DA, Fernandes A, Feusner JD, Fonzo GA, Fuentes-Claramonte P, Gaab N, Godlewska BR, Goldstein BI, Gonul AS, Gotlib IH, Grabe HJ, Green MJ, Grotegerd D, Gruber O, Gruner P, Gupta AR, Gur RC, Gur RE, Haar S, Hamilton JP, Haukvik UK, Henskens FA, Hinc AC, Hirano Y, Hu H, Hughes ME, Iasevoli F, Im Y, Ipser J, Jabbar Abdl Sattar Hamoudi H, Jack A, Janiri D, Janssen J, Jaspers-Fayer F, Jensen KM, Jin J, Kaiser S, Kamishikiryo T, Kang MJY, Karuk A, Kathmann N, Kennedy KG, Kim M, King JA, Kircher T, Klahn AL, Klein DN, Koch K, Kochunov P, Kushki A, Kwon JS, Lake MT, Landén M, Lazaro L, Lebedeva I, Leila N, Li M, Lochner C, Loughland CM, Luna B, Remnélius KL, MacIntosh BJ, Mancini M, Manfro GG, Marsh R, Martinez-Zalacain I, Mataix-Cols D, McDonald C, McGrath J, Menchon JM, Morgado P, Mowry BJ, Mujica-Parodi LR, Muñoz E, Muratori F, Murphy D, Mwangi B, Narayanaswamy JC, Narumoto J, Nerland S, Neufeld J, Newman BT, Nielsen JA, Nurmi EL, O’Neill J, OHearn KM, Okada G, Oranje B, Pantelis C, Parker N, Pelphrey KA, Phillips ML, Piacentini J, Picó-Pérez M, Picotin R, Pigoni A, Piras F, Piras F, Pomarol-Clotet E, Pontillo G, Porta-Casteràs D, Portella MJ, Price RB, Quidé Y, Radua J, Ringin E, Rodriguez-Cano E, Rokicki J, Romero-Garcia R, Rossell S, Ruan H, Rubia K, Sacchet MD, Sakai Y, Salvador R, Sani G, Sato JR, Schmidt A, Scott RJ, Sellgren CM, Sempach L, Shimizu E, Shivakumar V, Sim K, Soares JC, Soreni N, Soriano-Mas C, Sousa N, Stein F, Steinhäuser-Meerz JL, Stern ER, Straube T, Strawn JR, Sumner PJ, Sungur I, Szeszko PR, Tammimies K, Tomyshev AS, Tosetti M, van de Mortel LA, van Horn JD, van Nieuwenhuizen H, van Rheenen TE, van Wingen G, Vecchio D, Venkatasubramanian G, Vieta E, Vilajosana E, Vives-Gilabert Y, Völzke H, Vriend C, Wallace GL, Wang Z, Walter M, Wang L, Webb SJ, Westlye LT, Whittle S, Wielpütz MO, Wittfeld K, Woods W, Wu M, Yang TT, Yatham LN, Yoshida T, Yoshinari A, Yun J, Zhao Q, Zunta-Soares GB, ENIGMA Autism Working Group, ENIGMA Anxiety Working Group, ENIGMA Bipolar Disorder Working Group, ENIGMA Major Depression Working Group, ENIGMA OCD Working Group, ENIGMA Schizo.   +229 more
europepmc   +1 more source

Allelic structural variation at the NLR25-1 locus enhances defense against Pseudomonas syringae in kiwifruit. [PDF]

Genome Biol
Wu Y, Wang Y, Lin Y, Zhao M, Huo Y, Zhang T, Wang H, Zhu Y, Wang L, Zheng P, Yue J, Wang S, Liu Y.   +12 more
europepmc   +1 more source