Results 81 to 90 of about 1,047,704 (361)
The newfound relationship between extrachromosomal DNAs and excised signal circles
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Структуралізм як лінгвістична течія (Structuralism as a linguistic movement) [PDF]
Структуралізм як мовознавчий напрям з’явився відносно нещодавно, він потребує докладного та глибокого вивчення. У тезах досліджено основні положення структуралізму, Празька та Копенгагенська школа структуралізму, як осно- вних засновників ...
Бортнік, О. (O. Bortnik)
core
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman +2 more
wiley +1 more source
From structuralism to poststructuralism [PDF]
As the immediate precursor to poststructuralism, the movement or paradigm of structuralism was naturally responsible for determining many of poststructuralism’s salient features. But what was structuralism, and how are we to understand its transformation
Lundy, C
core
La fenomenología como estructuralismo genético natural
A menudo se ha presentado a la fenomenología y al estructuralismo como perspectivas contra puestas. Nos proponemos revisar esta confrontación. Argumentaremos que hubo cierta influencia de Husserl en el estructuralismo de principios del siglo XX, y que ...
Carlos Belvedere
doaj
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Categories without structures [PDF]
The popular view according to which Category theory provides a support for Mathematical Structuralism is erroneous. Category-theoretic foundations of mathematics require a different philosophy of mathematics.
Rodin, Andrei
core +5 more sources
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
The sctructuralismo as epistemology and method
The aim of this article is to illustrate the teachers, researchers, academics and students of the Human and Social Sciences, in a general view, but with distinctive features, about history, some theoretical foundations and some final considerations on ...
Luis Francisco Ochoa Rojas
doaj +1 more source
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source

