Results 51 to 60 of about 10,109,694 (374)
Semi-Synthesis of Harringtonolide Derivatives and Their Antiproliferative Activity
Molecules, 2021 Harringtonolide (HO), a natural product isolated from Cephalotaxus harringtonia, exhibits potent antiproliferative activity. However, little information has been reported on the systematic structure−activity relationship (SAR) of HO derivatives ...
Xiutao Wu +6 more
doaj +1 more source
Relationship structure-antioxidant activity of hindered phenolic compounds [PDF]
, 2014 The relationship between the structure and the antioxidant activity of 21 hindered phenolic compounds was investigated by Rancimat and DPPH· tests. 3-tert-butyl-5-methylbenzene-1,2-diol is the strongest antioxidant in the Rancimat test but not in the ...
King, X. C. Weng, Y. Huang
core +3 more sources
Drug Design, Development and Therapy, 2022 Lijing Wang College of Life Sciences and Technology, China Pharmaceutical University, Nanjing, Jiangsu, People’s Republic of ChinaCorrespondence: Lijing Wang, College of Life Science and Technology, China Pharmaceutical University, 639 Longmian ...
Wang L
doaj
Piperazine skeleton in the structural modification of natural products: a review
Journal of Enzyme Inhibition and Medicinal Chemistry, 2021 Piperazine moiety is a cyclic molecule containing two nitrogen atoms in positions 1 and 4, as well as four carbon atoms. Piperazine is one of the most sought heterocyclics for the development of new drug candidates with a wide range of applications. Over
Run-Hui Zhang +4 more
doaj +1 more source
Bulletin of Faculty of Pharmacy Cairo University, 2014 In the present study, a series of novel pyrimidines (1) and their thioethers (2–5) were synthesized. Structures of the synthesized compounds were established by IR, 1H NMR, 13C NMR mass spectral data and elemental analysis.
Chetan M. Bhalgat, B. Ramesh
doaj +1 more source
AVR: Attention based Salient Visual Relationship Detection [PDF]
arXiv, 2020 Visual relationship detection aims to locate objects in images and recognize the relationships between objects. Traditional methods treat all observed relationships in an image equally, which causes a relatively poor performance in the detection tasks on complex images with abundant visual objects and various relationships.
arxiv
Quantitative structure-activity relationship for antimalarial activity of artemisinin [PDF]
, 2010 The increase in resistance to older drugs and the emergence of new types of infection have created an urgent need for discovery and development of new compounds with antimalarial activity.
Hasan, Mohamed Noor +1 more
core
Structure-activity relationship of immunostimulatory effects of phthalates [PDF]
, 2008 Background Some chemicals, including some phthalate plasticizers, have been shown to have an adjuvant effect in mice. However, an adjuvant effect, defined as an inherent ability to stimulate the humoral immune response, was only observed after exposure ...
Larsen, Søren T, Nielsen, Gunnar D
core +3 more sources
Structure–activity relationship of ipglycermide binding to phosphoglycerate mutases [PDF]
, 2021 Catalysis of human phosphoglycerate mutase is dependent on a 2,3-bisphosphoglycerate cofactor (dPGM), whereas the nonhomologous isozyme in many parasitic species is cofactor independent (iPGM).
Aitha, Mahesh +14 more
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