Results 121 to 130 of about 5,517,395 (407)

Circulating tumor DNA (ctDNA) trajectories predict survival in trifluridine/tipiracil‐treated metastatic colorectal cancer patients

Molecular Oncology, EarlyView.
The authors applied joint/mixed models that predict mortality of trifluridine/tipiracil‐treated metastatic colorectal cancer patients based on circulating tumor DNA (ctDNA) trajectories. Patients at high risk of death could be spared aggressive therapy with the prospect of a higher quality of life in their remaining lifetime, whereas patients with a ...
Matthias Unseld, Stefan Kühberger, Ricarda Graf, Christine Beichler, Markus Braun, Nadia Dandachi, Ellen Heitzer, Gerald W. Prager   +7 more
wiley   +1 more source

The PTTG1/VASP axis promotes oral squamous cell carcinoma metastasis by modulating focal adhesion and actin filaments

Molecular Oncology, EarlyView.
VASP was found to be overexpressed in metastatic oral squamous cell carcinoma (OSCC) tissues. Notably, PTTG1‐ and VASP‐deficient OSCC cells demonstrated suppressed metastatic properties by disrupting the interaction between the cytoskeleton and focal adhesion (FAs) in the filopodia region.
Suyeon Park, Sang Shin Lee, Shihyun Kim, Yeonjun Lee, Gyeonwon Park, Jung Oh Kim, Jongho Choi   +6 more
wiley   +1 more source

Antimicrobial activity of quaternary ammonium salts: structure-activity relationship

Medicinal Chemistry Research, 2022
M. Nadagouda, P. Vijayasarathy, A. Sin, H. Nam, Sanaullah Khan, Javad B. M. Parambath, Ahmed Abouzeed Mohamed, Changseok Han   +7 more
semanticscholar   +1 more source

Metabolic profile and structure–activity relationship of resveratrol and its analogs in human bladder cancer cells

Cancer Management and Research, 2019
Yang Yang,1,2 Guangyuan Zhang,2 Chuangang Li,3 Sihan Wang,2 Manning Zhu,2 Jinan Wang,2 Hangtian Yue,2 Xiaodong Ma,2 Yuhong Zhen,2 Xiaohong Shu1,21College of Integrative Medicine, Dalian Medical University, Dalian 116044, People’s Republic of China;
Yang Y, Zhang G, Li C, Wang S, Zhu M, Wang J, Yue H, Ma X, Zhen Y, Shu X   +9 more
doaj  

The viscosity-radius relationship from scaling arguments [PDF]

arXiv, 2017
The viscosity-radius relationship for semi-dilute polymer solutions is derived using scaling arguments. The viscosity temperature and the temperature radius relationships are combined using the transitive equality relationship. The viscosity-radius relationship is determined to be .
arxiv  

Structure-activity relationship studies on O-sulfated Hirudins [PDF]

, 1998
Thesis (Ph. D. in Agriculture)--University of Tsukuba, (B), no.
Muramatsu Ryo, 村松 了
core  

Structure-Activity Relationship for the Oxadiazole Class of Antibiotics [PDF]

, 2015
The structure-activity relationship (SAR) for the newly discovered oxadiazole class of antibiotics is described with evaluation of 120 derivatives of the lead structure.
Antunes, Nuno T., Boudreau, Marc A., Chang, Mayland, Ding, Derong, Lastochkin, Elena, Leemans, Erika, Lichtenwalter, Katerina, Mobashery, Shahriar, O’Daniel, Peter I., Peng, Zhihong, Pi, Hualiang, Schroeder, Valerie A., Song, Wei, Spink, Edward, Suckow, Mark A., Testero, Sebastian Andres, Vakulenko, Sergei, Wolter, William R.   +17 more
core   +2 more sources

Aminothiazoles as Potent and Selective Sirt2 Inhibitors: A Structure-Activity Relationship Study.

Journal of Medicinal Chemistry, 2016
Sirtuins are NAD(+)-dependent protein deacylases that cleave off acetyl but also other acyl groups from the ε-amino group of lysines in histones and other substrate proteins.
M. Schiedel, Tobias Rumpf, Berin Karaman, A. Lehotzky, J. Olah, S. Gerhardt, J. Ovádi, W. Sippl, O. Einsle, M. Jung   +9 more
semanticscholar   +1 more source

Obesity alters the fitness of peritumoral adipose tissue, exacerbating tumor invasiveness in renal cancer through the induction of ADAM12 and CYP1B1

Molecular Oncology, EarlyView.
Tumor microenvironment drives cancer formation and progression. We analyzed the role of human cancer‐associated adipocytes from patients with renal cell carcinoma (RCC) stratified as lean, overweight, or obese. RNA‐seq demonstrated that, among the most altered genes involved in the tumor–stroma crosstalk, are ADAM12 and CYP1B1, which were proven to be ...
Sepehr Torabinejad, Caterina Miro, Annarita Nappi, Francesco Del Giudice, Annunziata Gaetana Cicatiello, Serena Sagliocchi, Lucia Acampora, Federica Restolfer, Melania Murolo, Emery Di Cicco, Federico Capone, Ciro Imbimbo, Monica Dentice, Felice Crocetto   +13 more
wiley   +1 more source

Relationship Between Structure And Antimicrobial Activity Of Zinc Oxide Nanoparticles: An Overview

International Journal of Nanomedicine, 2019
Bruna Lallo da Silva,1 Marina Paiva Abuçafy,1 Eloisa Berbel Manaia,1 João Augusto Oshiro Junior,1 Bruna Galdorfini Chiari-Andréo,1,2 Rosemeire CL R Pietro,1 Leila Aparecida Chiavacci1 1Department of Drugs and Medicines, School of ...
Lallo da Silva B, Abuçafy MP, Berbel Manaia E, Oshiro Junior JA, Chiari-Andréo BG, Pietro RCLR, Chiavacci LA   +6 more
doaj